FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2069122795> ?p ?o ?g. }

• W2069122795 endingPage "573" @default.
• W2069122795 startingPage "565" @default.
• W2069122795 abstract "Objective: HIV-infected persons have substantially higher risk of kidney failure than persons without HIV, but serum creatinine levels are insensitive for detecting declining kidney function. We hypothesized that urine markers of kidney injury would be associated with declining kidney function among HIV-infected women. Methods: In the Women's Interagency HIV Study, we measured concentrations of albumin-to-creatinine ratio, interleukin-18 (IL-18), kidney injury marker-1 (KIM-1), and neutrophil gelatinase-associated lipocalin from stored urine among 908 HIV-infected and 289 HIV-uninfected participants. Primary analyses used cystatin C-based estimated glomerular filtration rate (CKD-EPI eGFRcys) as the outcome, measured at baseline and 2 follow-up visits over 8 years; secondary analyses used creatinine (CKD-EPI eGFRcr). Each urine biomarker was categorized into tertiles, and kidney decline was modeled with both continuous and dichotomized outcomes. Results: Compared with the lowest tertiles, the highest tertiles of albumin-to-creatinine ratio (−0.15 mL/min per 1.73 m2, P < 0.0001), IL-18 (−0.09 mL/min per 1.73 m2, P < 0.0001) and KIM-1 (−0.06 mL/min per 1.73 m2, P < 0.001) were independently associated with faster eGFRcys decline after multivariate adjustment including all 3 biomarkers among HIV-infected women. Among these biomarkers, only IL-18 was associated with each dichotomized eGFRcys outcome: ≥3% (relative risk = 1.40; 95% confidence interval: 1.04 to 1.89); ≥5% (1.88; 1.30 to 2.71); and ≥10% (2.16; 1.20 to 3.88) for the highest versus lowest tertile. In alternative models using eGFRcr, the high tertile of KIM-1 had independent associations with 5% (1.71; 1.25 to 2.33) and 10% (1.78; 1.07 to 2.96) decline, and the high IL-18 tertile with 10% decline (1.97; 1.00 to 3.87). Conclusions: Among HIV-infected women in the Women's Interagency HIV Study cohort, novel urine markers of kidney injury detect risk for subsequent declines in kidney function." @default.
• W2069122795 created "2016-06-24" @default.
• W2069122795 creator A5002438645 @default.
• W2069122795 creator A5003081987 @default.
• W2069122795 creator A5029916378 @default.
• W2069122795 creator A5040529362 @default.
• W2069122795 creator A5048434963 @default.
• W2069122795 creator A5053346139 @default.
• W2069122795 creator A5056403325 @default.
• W2069122795 creator A5057443293 @default.
• W2069122795 creator A5058639364 @default.
• W2069122795 creator A5067731467 @default.
• W2069122795 creator A5071585977 @default.
• W2069122795 creator A5076361487 @default.
• W2069122795 creator A5083470674 @default.
• W2069122795 creator A5084477412 @default.
• W2069122795 creator A5086543280 @default.
• W2069122795 creator A5087652874 @default.
• W2069122795 date "2012-12-15" @default.
• W2069122795 modified "2023-10-17" @default.
• W2069122795 title "Urinary Markers of Kidney Injury and Kidney Function Decline in HIV-Infected Women" @default.
• W2069122795 cites W1965135809 @default.
• W2069122795 cites W1965737702 @default.
• W2069122795 cites W1967879506 @default.
• W2069122795 cites W1971392543 @default.
• W2069122795 cites W1975123490 @default.
• W2069122795 cites W1979321576 @default.
• W2069122795 cites W1979656743 @default.
• W2069122795 cites W1980585375 @default.
• W2069122795 cites W1983455184 @default.
• W2069122795 cites W1985198441 @default.
• W2069122795 cites W1995980728 @default.
• W2069122795 cites W2003056396 @default.
• W2069122795 cites W2020091161 @default.
• W2069122795 cites W2041736631 @default.
• W2069122795 cites W2048366382 @default.
• W2069122795 cites W2064052004 @default.
• W2069122795 cites W2064576408 @default.
• W2069122795 cites W2071066672 @default.
• W2069122795 cites W2072707986 @default.
• W2069122795 cites W2094234130 @default.
• W2069122795 cites W2107195787 @default.
• W2069122795 cites W2108650686 @default.
• W2069122795 cites W2108842111 @default.
• W2069122795 cites W2110614818 @default.
• W2069122795 cites W2115052886 @default.
• W2069122795 cites W2121036476 @default.
• W2069122795 cites W2121637153 @default.
• W2069122795 cites W2124770381 @default.
• W2069122795 cites W2128832729 @default.
• W2069122795 cites W2134127271 @default.
• W2069122795 cites W2135241380 @default.
• W2069122795 cites W2137004892 @default.
• W2069122795 cites W2141869612 @default.
• W2069122795 cites W2141876271 @default.
• W2069122795 cites W2145099862 @default.
• W2069122795 cites W2146901169 @default.
• W2069122795 cites W2165088763 @default.
• W2069122795 cites W3207530515 @default.
• W2069122795 cites W4230628259 @default.
• W2069122795 cites W4255535345 @default.
• W2069122795 cites W4378951505 @default.
• W2069122795 doi "https://doi.org/10.1097/qai.0b013e3182737706" @default.
• W2069122795 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3509242" @default.
• W2069122795 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23023103" @default.
• W2069122795 hasPublicationYear "2012" @default.
• W2069122795 type Work @default.
• W2069122795 sameAs 2069122795 @default.
• W2069122795 citedByCount "49" @default.
• W2069122795 countsByYear W20691227952013 @default.
• W2069122795 countsByYear W20691227952014 @default.
• W2069122795 countsByYear W20691227952015 @default.
• W2069122795 countsByYear W20691227952016 @default.
• W2069122795 countsByYear W20691227952017 @default.
• W2069122795 countsByYear W20691227952018 @default.
• W2069122795 countsByYear W20691227952019 @default.
• W2069122795 countsByYear W20691227952020 @default.
• W2069122795 countsByYear W20691227952021 @default.
• W2069122795 countsByYear W20691227952023 @default.
• W2069122795 crossrefType "journal-article" @default.
• W2069122795 hasAuthorship W2069122795A5002438645 @default.
• W2069122795 hasAuthorship W2069122795A5003081987 @default.
• W2069122795 hasAuthorship W2069122795A5029916378 @default.
• W2069122795 hasAuthorship W2069122795A5040529362 @default.
• W2069122795 hasAuthorship W2069122795A5048434963 @default.
• W2069122795 hasAuthorship W2069122795A5053346139 @default.
• W2069122795 hasAuthorship W2069122795A5056403325 @default.
• W2069122795 hasAuthorship W2069122795A5057443293 @default.
• W2069122795 hasAuthorship W2069122795A5058639364 @default.
• W2069122795 hasAuthorship W2069122795A5067731467 @default.
• W2069122795 hasAuthorship W2069122795A5071585977 @default.
• W2069122795 hasAuthorship W2069122795A5076361487 @default.
• W2069122795 hasAuthorship W2069122795A5083470674 @default.
• W2069122795 hasAuthorship W2069122795A5084477412 @default.
• W2069122795 hasAuthorship W2069122795A5086543280 @default.
• W2069122795 hasAuthorship W2069122795A5087652874 @default.
• W2069122795 hasBestOaLocation W20691227951 @default.
• W2069122795 hasConcept C126322002 @default.

• next