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- W2069127746 abstract "Abstract Eighty-five patients with clinical Stage I endometrial carcinoma were reviewed: 81% of patients had either pre-operative or post-operative radiotherapy (RT). The incidence of deep myometrial invasion (outer 13 of thickness) of pre-op RT vs. post-op RT group was 6% and 28% respectively; the pre-op irradiation seemed to alter the depth of myometrial invasion. Eleven patients (13%) developed recurrences: 9 of these patients (82%) had recurrences in the extrapelvis. The incidence of extrapelvic recurrence of patients with Grade 3 tumors was 29% (414); those with deep myometrial invasion was 33% (412). The overall 5 year survival and complication rate was 89% and 4% respectively: these results were comparable between pre-op RT and post-op RT groups. However, post-op RT offers the advantage of accurate surgical-pathologic staging and optimal individualization of adjuvant therapy. In addition, those who have deep myometrial invasion and/or Grade 3 tumors may require systemic therapy in view of high incidence of distant failures." @default.
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- W2069127746 date "1981-10-01" @default.
- W2069127746 modified "2023-09-27" @default.
- W2069127746 title "The role of adjunctive radiotherapy for stage I endometrial carcinoma: Preoperative vs postoperative irradiation" @default.
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- W2069127746 doi "https://doi.org/10.1016/0360-3016(81)90040-7" @default.
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