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- W2069170982 abstract "Optical methods allow investigating biological tissue noninvasively without ionizing radiations. Moreover, considering low absorption processes in the tissue in the near-infrared wavelengths range, biological tissue can be deeply investigated. In this field, we studied the resolution limits of the detection of one and two tumour-like heterogeneities embedded in the middle plane of a slab that mimics a breast enclosed between two transparent plates. We used the diffusion equation in order to model the photons propagation in such slab. It is solved in the time-domain by means of a finite element method. We computed time-resolved trans-illumination data based on lateral scan of the slab. The timedependent transmitted light, received at the opposite of the source, was transformed in the frequency-domain and the modulation and phase-shift of the signal are then obtained. The resulting phase-shift considering the embedded objects was analyzed versus the distance between the objects. Then, the resolution limits were estimated considering different modulation frequencies and a noise level. The overall combinations took into account a set of optical properties that mimics realistic optical properties for healthy breast tissue and tumours." @default.
- W2069170982 created "2016-06-24" @default.
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- W2069170982 date "2011-06-09" @default.
- W2069170982 modified "2023-09-23" @default.
- W2069170982 title "Resolution limits between objects embedded in breast-like slab using the optical frequency-domain method: a numerical approach" @default.
- W2069170982 doi "https://doi.org/10.1117/12.890002" @default.
- W2069170982 hasPublicationYear "2011" @default.
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