FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2069173610> ?p ?o ?g. }

• W2069173610 endingPage "365" @default.
• W2069173610 startingPage "359" @default.
• W2069173610 abstract "•MSCC is a common and devastating complication in CRPC patients. •Screening for MSCC is not performed, but men have regular staging CT scans. •We assessed CTs prior to MSCC for abnormal epidural and paravertebral signs. •Abnormal signs were visible in up to 80% of MSCC patients on prior CT scans. •Presence of these signs on CT should prompt consideration of MRI spine. Aim To test the hypothesis that computed tomography (CT)-based signs might precede symptomatic malignant spinal cord compression (MSCC) in men with metastatic castration-resistant prostate cancer (mCRPC). Materials and methods A database was used to identify suitable mCRPC patients. Staging CT images were retrospectively reviewed for signs preceding MSCC. Signs of malignant paravertebral fat infiltration and epidural soft-tissue disease were defined and assessed on serial CT in 34 patients with MSCC and 58 control patients. The presence and evolution of the features were summarized using descriptive statistics. Results In MSCC patients, CT performed a median of 28 days prior to the diagnostic magnetic resonance imaging (MRI) demonstrated significant epidural soft tissue in 28 (80%) patients. The median time to MSCC from a combination of overt malignant paravertebral and epidural disease was 2.7 (0–14.6) months. Conversely, these signs were uncommon in the control cohort. Conclusions Significant malignant paravertebral and/or epidural disease at CT precede MSCC in up to 80% of mCRPC patients and should prompt closer patient follow-up and consideration of early MRI evaluation. These CT-based features require further prospective validation. To test the hypothesis that computed tomography (CT)-based signs might precede symptomatic malignant spinal cord compression (MSCC) in men with metastatic castration-resistant prostate cancer (mCRPC). A database was used to identify suitable mCRPC patients. Staging CT images were retrospectively reviewed for signs preceding MSCC. Signs of malignant paravertebral fat infiltration and epidural soft-tissue disease were defined and assessed on serial CT in 34 patients with MSCC and 58 control patients. The presence and evolution of the features were summarized using descriptive statistics. In MSCC patients, CT performed a median of 28 days prior to the diagnostic magnetic resonance imaging (MRI) demonstrated significant epidural soft tissue in 28 (80%) patients. The median time to MSCC from a combination of overt malignant paravertebral and epidural disease was 2.7 (0–14.6) months. Conversely, these signs were uncommon in the control cohort. Significant malignant paravertebral and/or epidural disease at CT precede MSCC in up to 80% of mCRPC patients and should prompt closer patient follow-up and consideration of early MRI evaluation. These CT-based features require further prospective validation." @default.
• W2069173610 created "2016-06-24" @default.
• W2069173610 creator A5000156180 @default.
• W2069173610 creator A5003388016 @default.
• W2069173610 creator A5018210007 @default.
• W2069173610 creator A5040273298 @default.
• W2069173610 creator A5041581270 @default.
• W2069173610 creator A5053685449 @default.
• W2069173610 creator A5056339622 @default.
• W2069173610 creator A5062641751 @default.
• W2069173610 creator A5072378199 @default.
• W2069173610 creator A5079652931 @default.
• W2069173610 creator A5082144106 @default.
• W2069173610 creator A5088696108 @default.
• W2069173610 date "2015-04-01" @default.
• W2069173610 modified "2023-09-26" @default.
• W2069173610 title "Progressive computed tomography (CT) appearances preceding malignant spinal cord compression (MSCC) in men with castration-resistant prostate cancer" @default.
• W2069173610 cites W1968572686 @default.
• W2069173610 cites W2004706775 @default.
• W2069173610 cites W2028937729 @default.
• W2069173610 cites W2037898205 @default.
• W2069173610 cites W2063575508 @default.
• W2069173610 cites W2085910666 @default.
• W2069173610 cites W2110270180 @default.
• W2069173610 cites W2130771859 @default.
• W2069173610 cites W2134053341 @default.
• W2069173610 cites W2139860898 @default.
• W2069173610 cites W2145410559 @default.
• W2069173610 cites W2167331614 @default.
• W2069173610 cites W2317139673 @default.
• W2069173610 doi "https://doi.org/10.1016/j.crad.2014.05.104" @default.
• W2069173610 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25555314" @default.
• W2069173610 hasPublicationYear "2015" @default.
• W2069173610 type Work @default.
• W2069173610 sameAs 2069173610 @default.
• W2069173610 citedByCount "7" @default.
• W2069173610 countsByYear W20691736102016 @default.
• W2069173610 countsByYear W20691736102017 @default.
• W2069173610 countsByYear W20691736102018 @default.
• W2069173610 countsByYear W20691736102022 @default.
• W2069173610 countsByYear W20691736102023 @default.
• W2069173610 crossrefType "journal-article" @default.
• W2069173610 hasAuthorship W2069173610A5000156180 @default.
• W2069173610 hasAuthorship W2069173610A5003388016 @default.
• W2069173610 hasAuthorship W2069173610A5018210007 @default.
• W2069173610 hasAuthorship W2069173610A5040273298 @default.
• W2069173610 hasAuthorship W2069173610A5041581270 @default.
• W2069173610 hasAuthorship W2069173610A5053685449 @default.
• W2069173610 hasAuthorship W2069173610A5056339622 @default.
• W2069173610 hasAuthorship W2069173610A5062641751 @default.
• W2069173610 hasAuthorship W2069173610A5072378199 @default.
• W2069173610 hasAuthorship W2069173610A5079652931 @default.
• W2069173610 hasAuthorship W2069173610A5082144106 @default.
• W2069173610 hasAuthorship W2069173610A5088696108 @default.
• W2069173610 hasConcept C118552586 @default.
• W2069173610 hasConcept C121608353 @default.
• W2069173610 hasConcept C126322002 @default.
• W2069173610 hasConcept C126838900 @default.
• W2069173610 hasConcept C143409427 @default.
• W2069173610 hasConcept C2776235491 @default.
• W2069173610 hasConcept C2778231337 @default.
• W2069173610 hasConcept C2780192828 @default.
• W2069173610 hasConcept C2780775167 @default.
• W2069173610 hasConcept C71924100 @default.
• W2069173610 hasConceptScore W2069173610C118552586 @default.
• W2069173610 hasConceptScore W2069173610C121608353 @default.
• W2069173610 hasConceptScore W2069173610C126322002 @default.
• W2069173610 hasConceptScore W2069173610C126838900 @default.
• W2069173610 hasConceptScore W2069173610C143409427 @default.
• W2069173610 hasConceptScore W2069173610C2776235491 @default.
• W2069173610 hasConceptScore W2069173610C2778231337 @default.
• W2069173610 hasConceptScore W2069173610C2780192828 @default.
• W2069173610 hasConceptScore W2069173610C2780775167 @default.
• W2069173610 hasConceptScore W2069173610C71924100 @default.
• W2069173610 hasFunder F4320306163 @default.
• W2069173610 hasFunder F4320332898 @default.
• W2069173610 hasIssue "4" @default.
• W2069173610 hasLocation W20691736101 @default.
• W2069173610 hasLocation W20691736102 @default.
• W2069173610 hasOpenAccess W2069173610 @default.
• W2069173610 hasPrimaryLocation W20691736101 @default.
• W2069173610 hasRelatedWork W1980245127 @default.
• W2069173610 hasRelatedWork W2064643060 @default.
• W2069173610 hasRelatedWork W2112204372 @default.
• W2069173610 hasRelatedWork W2273540743 @default.
• W2069173610 hasRelatedWork W2400504790 @default.
• W2069173610 hasRelatedWork W2410191098 @default.
• W2069173610 hasRelatedWork W2413759219 @default.
• W2069173610 hasRelatedWork W2599589207 @default.
• W2069173610 hasRelatedWork W3005513856 @default.
• W2069173610 hasRelatedWork W3166118201 @default.
• W2069173610 hasVolume "70" @default.
• W2069173610 isParatext "false" @default.
• W2069173610 isRetracted "false" @default.
• W2069173610 magId "2069173610" @default.
• W2069173610 workType "article" @default.