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• W2069183085 abstract "Abstract. We studied neutrophil functions in a patient with colony-stimulating activity (CSA)-producing lung cancer. A 59-year-old man had an abnormal chest X-ray and leucocytosis, predominantly with neutrophils. Pneumonectomy was performed, and the histological diagnosis of the tumour was large-cell carcinoma of the lung. The tumour induced marked granulocytosis in tumour-transplanted nude mice, and the conditioned media of the tumour contained very strong human-active CSA. Superoxide release and membrane depolarization in neutrophils stimulated by the chemotactic peptide, N-formyl-methionyl-leucyl-phenylalanine, were markedly enhanced in the patient. These findings suggest that CSA produced by the tumour primed neutrophil functions in vivo in the patient." @default.
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• W2069183085 date "1991-11-01" @default.
• W2069183085 modified "2023-09-26" @default.
• W2069183085 title "Enhanced neutrophil functions in a patient with colony-stimulating activity-producing lung cancer" @default.
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• W2069183085 doi "https://doi.org/10.1111/j.1365-2796.1991.tb00473.x" @default.
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