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• W2069184525 abstract "Sialyl‐Lewis x (NeuAcα2→3Galβ1→4[Fucαl→3]GlcNAc] has been identified as a ligand for E‐selectin, P‐selectin and recently also for L‐selectin. We have synthesized the sialyl‐Lewis x tetrasaccharide by total enzymatic synthesis from N ‐acetyllactosamine using a placental α2→3‐sialyltransferase specific for type‐2 chain acceptors, followed by a cloned human α1→3‐fucosyltransferase (FucTV, the ‘plasma‐type’ enzyme). This procedure resulted in the tetrasaccharide in a 61% overall yield." @default.
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• W2069184525 date "1993-09-20" @default.
• W2069184525 modified "2023-10-18" @default.
• W2069184525 title "Efficient enzymatic synthesis of the sialyl‐Lewis^X tetrasaccharide" @default.
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• W2069184525 doi "https://doi.org/10.1016/0014-5793(93)80881-t" @default.
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