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- W2069194638 abstract "Abstract A series of analogs with the general structure N 1 -(substituted) pantothenamide has been prepared and studied in several microbiological systems. Certain of these derivatives were inhibitory to growth of lactic acid bacteria at concentrations as low as 6 μg/ml and to Escherichia coli at levels as low as 0.6 μg/ml. In Lactobacillus arabinosus and Pediococcus cerevisiae the analogs were competitively reversed by pantothenic acid with inhibition indices between 30 and 300. Inhibition of growth by the analogs in E. coli is of particular interest since previous potential pantothenic acid antimetabolites have been relatively inactive for this microorganism." @default.
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- W2069194638 date "1970-04-01" @default.
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- W2069194638 title "N1-(substituted) pantothenamides, antimetabolites of pantothenic acid" @default.
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- W2069194638 doi "https://doi.org/10.1016/0003-9861(70)90470-4" @default.
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