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- W2069209649 abstract "T he years of 1902-1903 are marked by Einthoven’s publication’ of the first surface electrocardiograms which, for all practical considerations, may be called undistorted (Fig. 1). Before and after this date it has been recognized that the electrical variations recorded from the surface of a body are composite in nature. Consequently, much effort has been made to obtain the potential-time course from the site of its origin: the surface membrane of cardiac fibers. In 1X83, BurdonSanderson and Page2 were leading off between an injured and a noninjured spot of the frog or tortoise heart and obtained the first “monophasic” records by means of a fast moving capillary electrometer. Such tracings are currently interpreted to reflect the variations taking place in the intact part of the heart; it is assumed that the damaged region makes no contribution. Schtitz, in 1929, found the means to keep one spot injured “permanently” by the combined effect of a ligature and suction. This technique made it possible to obtain reproducible records over longer periods of time and gave rise to systematic investigation of the monophasic action potential under a variety of conditions.3" @default.
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- W2069209649 date "1961-03-01" @default.
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- W2069209649 title "Ion movements underlying the cardiac action potential" @default.
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- W2069209649 doi "https://doi.org/10.1016/0002-8703(61)90598-1" @default.
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