Matches in SemOpenAlex for { <https://semopenalex.org/work/W2069258977> ?p ?o ?g. }
- W2069258977 endingPage "940" @default.
- W2069258977 startingPage "936" @default.
- W2069258977 abstract "To examine the prognostic value of percent positive cores (PPC) in prostate cancer patients treated with external beam radiotherapy (RT).An institutional review board-approved, retrospective analysis was conducted on 814 patients treated with RT with or without hormonal therapy between 1984 and 2002. Percent positive cores (number of positive cores divided by total number of cores) was calculable for 591 patients with a median follow-up of 65 months. Univariate and multivariable analyses were performed using Kaplan-Meier and Cox proportional hazard methods relating PPC to other risk factors, biochemical/clinical disease-free survival (PSA-DFS), prostate cancer-specific survival (DSS), and overall survival (OS).Percent positive cores was associated with stage, Gleason score (GS), pretreatment serum prostate-specific antigen (PSA) level, and use of adjunctive androgen suppression therapy. The 5-year PSA-DFS, DSS, and OS rates were 80%, 99%, and 91%, respectively, for patients with PPC less than 50%, compared with 56%, 94%, and 87% for patients with PPC 50% or greater (P <0.0001, <0.004, and <0.04, respectively). Multivariable analysis revealed that PPC, stage, GS, PSA, and androgen suppression therapy were all significantly associated with PSA-DFS, whereas only GS was associated with DSS and OS. For high, intermediate, and low-risk patients, 5-year PSA-DFS was 62% versus 39%, 80% versus 59%, and 90% versus 82% for PPC less than 50% versus PPC 50% or greater, respectively.Percent positive cores predicts outcome of prostate cancer patients treated with RT, independently of other known prognostic factors. Percent positive cores may have particular use for further risk stratification within established clinical risk categories." @default.
- W2069258977 created "2016-06-24" @default.
- W2069258977 creator A5009369151 @default.
- W2069258977 creator A5019390129 @default.
- W2069258977 creator A5037164513 @default.
- W2069258977 creator A5045162411 @default.
- W2069258977 creator A5063913503 @default.
- W2069258977 creator A5087998003 @default.
- W2069258977 date "2007-05-01" @default.
- W2069258977 modified "2023-10-07" @default.
- W2069258977 title "Percent Positive Biopsy Cores as a Prognostic Factor for Prostate Cancer Treated with External Beam Radiation" @default.
- W2069258977 cites W1978216056 @default.
- W2069258977 cites W1986065418 @default.
- W2069258977 cites W2077209997 @default.
- W2069258977 cites W2081292833 @default.
- W2069258977 cites W2090262881 @default.
- W2069258977 cites W2091957026 @default.
- W2069258977 cites W2106497063 @default.
- W2069258977 cites W2107318095 @default.
- W2069258977 cites W2114251516 @default.
- W2069258977 cites W2117792530 @default.
- W2069258977 cites W2117849419 @default.
- W2069258977 cites W2135106735 @default.
- W2069258977 cites W2141874849 @default.
- W2069258977 cites W2149871332 @default.
- W2069258977 cites W2152561234 @default.
- W2069258977 cites W2154293809 @default.
- W2069258977 cites W2209020482 @default.
- W2069258977 doi "https://doi.org/10.1016/j.urology.2007.01.066" @default.
- W2069258977 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17482938" @default.
- W2069258977 hasPublicationYear "2007" @default.
- W2069258977 type Work @default.
- W2069258977 sameAs 2069258977 @default.
- W2069258977 citedByCount "37" @default.
- W2069258977 countsByYear W20692589772012 @default.
- W2069258977 countsByYear W20692589772013 @default.
- W2069258977 countsByYear W20692589772014 @default.
- W2069258977 countsByYear W20692589772015 @default.
- W2069258977 countsByYear W20692589772016 @default.
- W2069258977 countsByYear W20692589772018 @default.
- W2069258977 countsByYear W20692589772019 @default.
- W2069258977 countsByYear W20692589772020 @default.
- W2069258977 countsByYear W20692589772021 @default.
- W2069258977 countsByYear W20692589772023 @default.
- W2069258977 crossrefType "journal-article" @default.
- W2069258977 hasAuthorship W2069258977A5009369151 @default.
- W2069258977 hasAuthorship W2069258977A5019390129 @default.
- W2069258977 hasAuthorship W2069258977A5037164513 @default.
- W2069258977 hasAuthorship W2069258977A5045162411 @default.
- W2069258977 hasAuthorship W2069258977A5063913503 @default.
- W2069258977 hasAuthorship W2069258977A5087998003 @default.
- W2069258977 hasConcept C121608353 @default.
- W2069258977 hasConcept C126322002 @default.
- W2069258977 hasConcept C126894567 @default.
- W2069258977 hasConcept C143998085 @default.
- W2069258977 hasConcept C144301174 @default.
- W2069258977 hasConcept C146357865 @default.
- W2069258977 hasConcept C151730666 @default.
- W2069258977 hasConcept C207103383 @default.
- W2069258977 hasConcept C2776235491 @default.
- W2069258977 hasConcept C2778311097 @default.
- W2069258977 hasConcept C2780192828 @default.
- W2069258977 hasConcept C2781406297 @default.
- W2069258977 hasConcept C38180746 @default.
- W2069258977 hasConcept C44249647 @default.
- W2069258977 hasConcept C50382708 @default.
- W2069258977 hasConcept C509974204 @default.
- W2069258977 hasConcept C71924100 @default.
- W2069258977 hasConcept C86803240 @default.
- W2069258977 hasConceptScore W2069258977C121608353 @default.
- W2069258977 hasConceptScore W2069258977C126322002 @default.
- W2069258977 hasConceptScore W2069258977C126894567 @default.
- W2069258977 hasConceptScore W2069258977C143998085 @default.
- W2069258977 hasConceptScore W2069258977C144301174 @default.
- W2069258977 hasConceptScore W2069258977C146357865 @default.
- W2069258977 hasConceptScore W2069258977C151730666 @default.
- W2069258977 hasConceptScore W2069258977C207103383 @default.
- W2069258977 hasConceptScore W2069258977C2776235491 @default.
- W2069258977 hasConceptScore W2069258977C2778311097 @default.
- W2069258977 hasConceptScore W2069258977C2780192828 @default.
- W2069258977 hasConceptScore W2069258977C2781406297 @default.
- W2069258977 hasConceptScore W2069258977C38180746 @default.
- W2069258977 hasConceptScore W2069258977C44249647 @default.
- W2069258977 hasConceptScore W2069258977C50382708 @default.
- W2069258977 hasConceptScore W2069258977C509974204 @default.
- W2069258977 hasConceptScore W2069258977C71924100 @default.
- W2069258977 hasConceptScore W2069258977C86803240 @default.
- W2069258977 hasIssue "5" @default.
- W2069258977 hasLocation W20692589771 @default.
- W2069258977 hasLocation W20692589772 @default.
- W2069258977 hasOpenAccess W2069258977 @default.
- W2069258977 hasPrimaryLocation W20692589771 @default.
- W2069258977 hasRelatedWork W2031954916 @default.
- W2069258977 hasRelatedWork W2069525082 @default.
- W2069258977 hasRelatedWork W2137157171 @default.
- W2069258977 hasRelatedWork W2381163510 @default.
- W2069258977 hasRelatedWork W2395586933 @default.
- W2069258977 hasRelatedWork W2744105963 @default.