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- W2069308265 abstract "Trabectedin is the first marine-derived anti-neoplastic drug approved for the treatment of advanced soft tissue sarcoma and, in combination with pegylated liposomal doxorubicin, for the treatment of patients with relapsed platinum-sensitive ovarian cancer. From the beginning of its development, trabectedin showed some peculiar properties that clearly distinguished it from other anti-cancer drugs. In this mini-review, we will outline the current state of knowledge regarding the mode of action of trabectedin, which appears to represent a new class of anti-neoplastic drugs acting both on cancer cells and on the tumour microenvironment." @default.
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- W2069308265 date "2014-04-22" @default.
- W2069308265 modified "2023-10-13" @default.
- W2069308265 title "Trabectedin, a drug acting on both cancer cells and the tumour microenvironment" @default.
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- W2069308265 doi "https://doi.org/10.1038/bjc.2014.149" @default.
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