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• W2069356814 abstract "A stem cell niche is a microenvironment that supports self-renewal of a population of stem cells, and their production of differentiated cells. While the definition evokes images of a stem cell Shangri-La-where a serene stem cell pool nestles within a niche that shelters and sustains it-the reality is much more tumultuous. Niches are subject to an ever-changing maelstrom of environmental factors, the ravages of old age, and the sly tactics of disease. Presented here is a basic overview of the different ways in which stem cell niches respond to local and systemic environments, and their impact on stem cell behavior. The primer culminates with a discussion of the topic with stem cell and niche biologists D. Leanne Jones, Ph.D., and Tudorita Tumbar, Ph.D." @default.
• W2069356814 created "2016-06-24" @default.
• W2069356814 creator A5023459370 @default.
• W2069356814 date "2011-02-14" @default.
• W2069356814 modified "2023-09-27" @default.
• W2069356814 title "Primer and interviews: The dynamic stem cell niche" @default.
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• W2069356814 doi "https://doi.org/10.1002/dvdy.22566" @default.
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