FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2069388204> ?p ?o ?g. }

• W2069388204 abstract "Introduction: Access to nuclear medicine department and sentinel node imaging remain an issue in number of hospitals. Preoperative Scintigrams are performed to confirm uptake of radioactivity and localisation of nodes in centres where facilities are available. Sentinella® (Oncovision, Valencia, Spain) is a recently introduced portable imaging gamma camera used intraoperatively to produce real time visual localisation of SLNs. Sentinella® was tested in a controlled laboratory environment and we report the first use of this technique in breast cancer patients from UK. Methods: In the laboratory setting our aim was to compare the sensitivity and spatial resolution of the Sentinella® and a conventional gamma camera (cGC) used for sentinel node imaging by comparing it with the performance of a GE multi-purpose rectangular (MPR) conventional single head gamma camera normally used for sentinel node imaging. A simulator containing seeds 10kBq, 100kBq, 500kBq of radiocolloid Tc, mimicking SLN, were used. Seeds were placed at several depths in the axilla, at 3cm, 5cm and 8cm from the skin. Sentinella was placed first at 10cm and then 1cm away from the axilla and images were recorded at 1min and at 2.5min for every position. The cGC was placed 20 cm away from the simulator. Results: 68 Sentinella® images and 34 cGC images obtained from the simulated axilla. Sentinella® resolution is comparable with the cGC for objects close to the camera i.e. ∼ 5 cm, but reduces rapidly as it9s moved away from the camera. For distances up to about 7 cm the Sentinella® with the blue collimator is more sensitive than the cGC. Sentinella detects high radioactivity (500 kBq) faster than cGC (1 vs 2.5min). In cases of low radioactivity (10kBq) Sentinella® was equally accurate and faster than cGC, when placed close to the skin. Identification of different number of beads with varying radioactivity was similar in Sentinella and cGC. Sentinella scans of the axilla were obtained in 85 patients undergoing SLNB. All patients had a preoperative lymphoscintigram. Serial Sentinella scans were obtained after removal of every hot node. Sentinella scans correlated with all the lymphoscintigrams in the 85 cases studied. Serial decay in activity was seen with removal of every hot node. Extra nodes were picked up in 6/85 cases after the axilla was found silent using hand held gamma probe. In 2/85 cases extra nodes found had cancer that led to axillary clearance. Sentinella scans were extremely useful in differentiating between a hot sentinel node and signal from injection site in upper outer quadrants of small sized breasts. Conclusion: Sentinella is accurate and fast in detecting radioactivity in the axilla. The anatomical shape of its collimator allows the operator to place it close to the axilla thus increasing sensitivity in cases of low radioactivity. Our independent tests and initial patient data confirm the excellent sensitivity and specificity. It9s major advantage is that it can be used by surgeons to scan for residual nodes before completion of the procedure. It can resolve the problem of centres that do not have nuclear medicine departments. This portable gamma camera can definitely replace the use of conventional lymphoscintigrams saving time and money both for patients and the Hospital. Citation Information: Cancer Res 2013;73(24 Suppl): Abstract nr P1-01-20." @default.
• W2069388204 created "2016-06-24" @default.
• W2069388204 creator A5008161954 @default.
• W2069388204 creator A5009970569 @default.
• W2069388204 creator A5010194993 @default.
• W2069388204 creator A5010840415 @default.
• W2069388204 creator A5022548720 @default.
• W2069388204 creator A5055983952 @default.
• W2069388204 creator A5079420496 @default.
• W2069388204 creator A5082431165 @default.
• W2069388204 creator A5089023827 @default.
• W2069388204 date "2013-12-15" @default.
• W2069388204 modified "2023-09-27" @default.
• W2069388204 title "Abstract P1-01-20: Intra-operative sentinel node imaging with a portable gamma camera in breast cancer" @default.
• W2069388204 doi "https://doi.org/10.1158/0008-5472.sabcs13-p1-01-20" @default.
• W2069388204 hasPublicationYear "2013" @default.
• W2069388204 type Work @default.
• W2069388204 sameAs 2069388204 @default.
• W2069388204 citedByCount "0" @default.
• W2069388204 crossrefType "proceedings-article" @default.
• W2069388204 hasAuthorship W2069388204A5008161954 @default.
• W2069388204 hasAuthorship W2069388204A5009970569 @default.
• W2069388204 hasAuthorship W2069388204A5010194993 @default.
• W2069388204 hasAuthorship W2069388204A5010840415 @default.
• W2069388204 hasAuthorship W2069388204A5022548720 @default.
• W2069388204 hasAuthorship W2069388204A5055983952 @default.
• W2069388204 hasAuthorship W2069388204A5079420496 @default.
• W2069388204 hasAuthorship W2069388204A5082431165 @default.
• W2069388204 hasAuthorship W2069388204A5089023827 @default.
• W2069388204 hasConcept C120665830 @default.
• W2069388204 hasConcept C121332964 @default.
• W2069388204 hasConcept C121608353 @default.
• W2069388204 hasConcept C126322002 @default.
• W2069388204 hasConcept C154945302 @default.
• W2069388204 hasConcept C179671157 @default.
• W2069388204 hasConcept C205372480 @default.
• W2069388204 hasConcept C2776608951 @default.
• W2069388204 hasConcept C2779200277 @default.
• W2069388204 hasConcept C2779610220 @default.
• W2069388204 hasConcept C2780212769 @default.
• W2069388204 hasConcept C2989005 @default.
• W2069388204 hasConcept C41008148 @default.
• W2069388204 hasConcept C530470458 @default.
• W2069388204 hasConcept C71924100 @default.
• W2069388204 hasConceptScore W2069388204C120665830 @default.
• W2069388204 hasConceptScore W2069388204C121332964 @default.
• W2069388204 hasConceptScore W2069388204C121608353 @default.
• W2069388204 hasConceptScore W2069388204C126322002 @default.
• W2069388204 hasConceptScore W2069388204C154945302 @default.
• W2069388204 hasConceptScore W2069388204C179671157 @default.
• W2069388204 hasConceptScore W2069388204C205372480 @default.
• W2069388204 hasConceptScore W2069388204C2776608951 @default.
• W2069388204 hasConceptScore W2069388204C2779200277 @default.
• W2069388204 hasConceptScore W2069388204C2779610220 @default.
• W2069388204 hasConceptScore W2069388204C2780212769 @default.
• W2069388204 hasConceptScore W2069388204C2989005 @default.
• W2069388204 hasConceptScore W2069388204C41008148 @default.
• W2069388204 hasConceptScore W2069388204C530470458 @default.
• W2069388204 hasConceptScore W2069388204C71924100 @default.
• W2069388204 hasLocation W20693882041 @default.
• W2069388204 hasOpenAccess W2069388204 @default.
• W2069388204 hasPrimaryLocation W20693882041 @default.
• W2069388204 hasRelatedWork W1953491320 @default.
• W2069388204 hasRelatedWork W2009007537 @default.
• W2069388204 hasRelatedWork W2052124718 @default.
• W2069388204 hasRelatedWork W2087926997 @default.
• W2069388204 hasRelatedWork W2119610470 @default.
• W2069388204 hasRelatedWork W2128158781 @default.
• W2069388204 hasRelatedWork W2164319639 @default.
• W2069388204 hasRelatedWork W2404208767 @default.
• W2069388204 hasRelatedWork W2518264310 @default.
• W2069388204 hasRelatedWork W2607927419 @default.
• W2069388204 hasRelatedWork W2969043027 @default.
• W2069388204 hasRelatedWork W58325655 @default.
• W2069388204 isParatext "false" @default.
• W2069388204 isRetracted "false" @default.
• W2069388204 magId "2069388204" @default.
• W2069388204 workType "article" @default.