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- W2069432857 abstract "The thyroid/serum radioiodide concentration ratio (T/S) of rats receiving thiouracil (TU) was depressed to a significantly greater degree by treatment with triiodothyronine (T3) than by hypophysectomy. Differences in iodine intake did not account for this finding. T3 failed to lower the T/S (>6) of hypophysectomized rats which were given TU, whereas in unoperated rats on a TU regimen the same dose of T3 reduced the T/S to 1. It is concluded that in addition to its inhibiting effect on thyrotrophin production T3 can also interfere with thyroidal iodide concentrating by another mechanism involving the pituitary in a mediating or permissive capacity." @default.
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- W2069432857 date "1959-07-01" @default.
- W2069432857 modified "2023-09-23" @default.
- W2069432857 title "INHIBITION OF THYROIDAL IODIDE CONCENTRATING BY TRIIODOTHYRONINE: EVIDENCE FOR AN EFFECT NOT DUE TO DEPRESSION OF THYROTROPHIN BUT DEPENDENT ON THE PITUITARY1" @default.
- W2069432857 doi "https://doi.org/10.1210/endo-65-1-101" @default.
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