Matches in SemOpenAlex for { <https://semopenalex.org/work/W2069449281> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2069449281 abstract "The effect of anti-mouse interferon (IFN) antibody on the course of genital herpes infection was studied in C57B1/6J mice. As we have previously described, intravaginal inoculation of C57 mice with herpes simplex virus type 2 (HSV-2) results in the development of genital lesions, subsequent encephalitis and death, with the mortality rate dependent on virus dose. In the present study, we found that intravaginal application of 1 x 10(5) units of anti-mouse (alpha/beta) IFN antibody did not significantly affect the course of infection. However, intraperitoneal or intravenous injection (the latter to a lesser extent) of anti-IFN antibody resulted in increased morbidity and mortality. In addition, intraperitoneal injection of anti-IFN antibody decreased the level of detectable endogenous IFN in peripheral blood and at the site of infection. The clear effect of anti-IFN antibody during early stages of infection points to the possible significance of early endogenous IFN production in ameliorating HSV-2 genital infection." @default.
- W2069449281 created "2016-06-24" @default.
- W2069449281 creator A5031514997 @default.
- W2069449281 creator A5055902964 @default.
- W2069449281 creator A5073134777 @default.
- W2069449281 date "1986-02-01" @default.
- W2069449281 modified "2023-10-14" @default.
- W2069449281 title "Effect of antibody to interferon on genital herpesvirus infection in mice" @default.
- W2069449281 cites W1153808763 @default.
- W2069449281 cites W1492834679 @default.
- W2069449281 cites W1822722295 @default.
- W2069449281 cites W1900079022 @default.
- W2069449281 cites W1985537838 @default.
- W2069449281 cites W2038965275 @default.
- W2069449281 cites W2050337487 @default.
- W2069449281 cites W2054241730 @default.
- W2069449281 cites W2074115964 @default.
- W2069449281 cites W2076118869 @default.
- W2069449281 cites W2089193554 @default.
- W2069449281 cites W2104527114 @default.
- W2069449281 cites W2130492874 @default.
- W2069449281 cites W2138427474 @default.
- W2069449281 cites W2211531029 @default.
- W2069449281 cites W2414738535 @default.
- W2069449281 doi "https://doi.org/10.1016/0882-4010(86)90033-1" @default.
- W2069449281 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3508484" @default.
- W2069449281 hasPublicationYear "1986" @default.
- W2069449281 type Work @default.
- W2069449281 sameAs 2069449281 @default.
- W2069449281 citedByCount "4" @default.
- W2069449281 crossrefType "journal-article" @default.
- W2069449281 hasAuthorship W2069449281A5031514997 @default.
- W2069449281 hasAuthorship W2069449281A5055902964 @default.
- W2069449281 hasAuthorship W2069449281A5073134777 @default.
- W2069449281 hasConcept C134018914 @default.
- W2069449281 hasConcept C159047783 @default.
- W2069449281 hasConcept C159654299 @default.
- W2069449281 hasConcept C16613235 @default.
- W2069449281 hasConcept C183021626 @default.
- W2069449281 hasConcept C203014093 @default.
- W2069449281 hasConcept C2522874641 @default.
- W2069449281 hasConcept C2776178377 @default.
- W2069449281 hasConcept C2778498788 @default.
- W2069449281 hasConcept C2780159080 @default.
- W2069449281 hasConcept C2781196997 @default.
- W2069449281 hasConcept C54355233 @default.
- W2069449281 hasConcept C83455156 @default.
- W2069449281 hasConcept C86803240 @default.
- W2069449281 hasConceptScore W2069449281C134018914 @default.
- W2069449281 hasConceptScore W2069449281C159047783 @default.
- W2069449281 hasConceptScore W2069449281C159654299 @default.
- W2069449281 hasConceptScore W2069449281C16613235 @default.
- W2069449281 hasConceptScore W2069449281C183021626 @default.
- W2069449281 hasConceptScore W2069449281C203014093 @default.
- W2069449281 hasConceptScore W2069449281C2522874641 @default.
- W2069449281 hasConceptScore W2069449281C2776178377 @default.
- W2069449281 hasConceptScore W2069449281C2778498788 @default.
- W2069449281 hasConceptScore W2069449281C2780159080 @default.
- W2069449281 hasConceptScore W2069449281C2781196997 @default.
- W2069449281 hasConceptScore W2069449281C54355233 @default.
- W2069449281 hasConceptScore W2069449281C83455156 @default.
- W2069449281 hasConceptScore W2069449281C86803240 @default.
- W2069449281 hasLocation W20694492811 @default.
- W2069449281 hasLocation W20694492812 @default.
- W2069449281 hasOpenAccess W2069449281 @default.
- W2069449281 hasPrimaryLocation W20694492811 @default.
- W2069449281 hasRelatedWork W1216818152 @default.
- W2069449281 hasRelatedWork W1561127041 @default.
- W2069449281 hasRelatedWork W1861653474 @default.
- W2069449281 hasRelatedWork W1993052581 @default.
- W2069449281 hasRelatedWork W2016164090 @default.
- W2069449281 hasRelatedWork W2026370556 @default.
- W2069449281 hasRelatedWork W2063955862 @default.
- W2069449281 hasRelatedWork W2095323469 @default.
- W2069449281 hasRelatedWork W2409733744 @default.
- W2069449281 hasRelatedWork W4249570160 @default.
- W2069449281 isParatext "false" @default.
- W2069449281 isRetracted "false" @default.
- W2069449281 magId "2069449281" @default.
- W2069449281 workType "article" @default.