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- W2069465462 abstract "A new liquid chromatographic procedure for the determination of phenobarbital in plasma samples is described. The proposed system uses a Spherisorb octadecyl-silane ODS-2 C18 analytical column, a guard column of similar characteristics, and a 0.03 M CTAB–3% 1-propanol at pH 7 mobile phase. The UV detector was set at 250 nm. Butabarbital was used as internal standard. Sample preparation only required the addition to the plasma samples of a 0.1 M SDS solution at pH 3 and centrifugation before injection into the chromatographic system. The limit of detection was 0.83 µg/mL of phenobarbital in plasma samples. The coefficients of variation were lower than 7.5%. Copyright © 2000 John Wiley & Sons, Ltd." @default.
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- W2069465462 date "2000-04-01" @default.
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- W2069465462 title "Determination of phenobarbital in plasma by micellar liquid chromatography" @default.
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- W2069465462 doi "https://doi.org/10.1002/(sici)1099-0801(200004)14:2<113::aid-bmc935>3.0.co;2-5" @default.
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