FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2069483518> ?p ?o ?g. }

• W2069483518 endingPage "3414" @default.
• W2069483518 startingPage "3398" @default.
• W2069483518 abstract "The major objective of this study was: discriminatory assessment of dry powder aerosol performance using standardized entrainment tubes (SETs) and lactose-based formulations with two model drugs. Drug/lactose interactive physical mixtures (2%w/w) were prepared. Their properties were measured: solid-state characterization of phase behavior and molecular interactions by differential scanning calorimetry and X-ray powder diffraction; particle morphology and size by scanning electron microscopy and laser diffraction; aerosol generation by SETs and characterization by twin-stage liquid impinger and Andersen cascade impactor operated at 60 L/min. The fine particle fraction (FPF) was correlated with SET shear stress (tau(s)), using a novel powder aerosol deaggregation equation (PADE). Drug particles were <5 microm in volume diameter with narrow unimodal distribution (Span <1). The lowest shear SET (tau(s) = 0.624 N/m(2)) gave a higher emitted dose (ED approximately 84-93%) and lower FPF (FPF(6.4) approximately 7-25%). In contrast, the highest shear SET (tau(s) = 13.143 N/m(2)) gave a lower ED (ED approximately 75-89%) and higher FPF (FPF(6.4) approximately 15-46%). The performance of disodium cromoglycate was superior to albuterol sulfate at given tau(s), as was milled with respect to sieved lactose monohydrate. Excellent correlation was observed (R(2) approximately 0.9804-0.9998) when pulmonary drug particle release from the surface of lactose carriers was interpreted by PADE linear regression for dry powder formulation evaluation and performance prediction." @default.
• W2069483518 created "2016-06-24" @default.
• W2069483518 creator A5007270786 @default.
• W2069483518 creator A5007994819 @default.
• W2069483518 creator A5017505062 @default.
• W2069483518 creator A5046356395 @default.
• W2069483518 creator A5071846305 @default.
• W2069483518 creator A5073471414 @default.
• W2069483518 date "2010-08-01" @default.
• W2069483518 modified "2023-09-23" @default.
• W2069483518 title "Dry Powder Aerosols Generated by Standardized Entrainment Tubes From Drug Blends With Lactose Monohydrate: 1. Albuterol Sulfate and Disodium Cromoglycate" @default.
• W2069483518 cites W129419657 @default.
• W2069483518 cites W1967397720 @default.
• W2069483518 cites W2001132794 @default.
• W2069483518 cites W2002227908 @default.
• W2069483518 cites W2006759883 @default.
• W2069483518 cites W2007029994 @default.
• W2069483518 cites W2009528099 @default.
• W2069483518 cites W2015698622 @default.
• W2069483518 cites W2029582129 @default.
• W2069483518 cites W2035061409 @default.
• W2069483518 cites W2037983079 @default.
• W2069483518 cites W2043599529 @default.
• W2069483518 cites W2048995438 @default.
• W2069483518 cites W2056301226 @default.
• W2069483518 cites W2058357714 @default.
• W2069483518 cites W2062398284 @default.
• W2069483518 cites W2081441319 @default.
• W2069483518 cites W2082203116 @default.
• W2069483518 cites W2086224770 @default.
• W2069483518 cites W2090115123 @default.
• W2069483518 cites W2104483548 @default.
• W2069483518 cites W2108837856 @default.
• W2069483518 cites W2122216165 @default.
• W2069483518 cites W2130384587 @default.
• W2069483518 cites W2134187187 @default.
• W2069483518 cites W2140459844 @default.
• W2069483518 cites W2232055132 @default.
• W2069483518 doi "https://doi.org/10.1002/jps.22107" @default.
• W2069483518 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20198688" @default.
• W2069483518 hasPublicationYear "2010" @default.
• W2069483518 type Work @default.
• W2069483518 sameAs 2069483518 @default.
• W2069483518 citedByCount "31" @default.
• W2069483518 countsByYear W20694835182012 @default.
• W2069483518 countsByYear W20694835182013 @default.
• W2069483518 countsByYear W20694835182014 @default.
• W2069483518 countsByYear W20694835182015 @default.
• W2069483518 countsByYear W20694835182016 @default.
• W2069483518 countsByYear W20694835182018 @default.
• W2069483518 countsByYear W20694835182019 @default.
• W2069483518 countsByYear W20694835182021 @default.
• W2069483518 countsByYear W20694835182022 @default.
• W2069483518 crossrefType "journal-article" @default.
• W2069483518 hasAuthorship W2069483518A5007270786 @default.
• W2069483518 hasAuthorship W2069483518A5007994819 @default.
• W2069483518 hasAuthorship W2069483518A5017505062 @default.
• W2069483518 hasAuthorship W2069483518A5046356395 @default.
• W2069483518 hasAuthorship W2069483518A5071846305 @default.
• W2069483518 hasAuthorship W2069483518A5073471414 @default.
• W2069483518 hasConcept C113196181 @default.
• W2069483518 hasConcept C121332964 @default.
• W2069483518 hasConcept C126322002 @default.
• W2069483518 hasConcept C147789679 @default.
• W2069483518 hasConcept C178790620 @default.
• W2069483518 hasConcept C185592680 @default.
• W2069483518 hasConcept C187530423 @default.
• W2069483518 hasConcept C192562407 @default.
• W2069483518 hasConcept C199289684 @default.
• W2069483518 hasConcept C2776042228 @default.
• W2069483518 hasConcept C2777419714 @default.
• W2069483518 hasConcept C2778724459 @default.
• W2069483518 hasConcept C2779345167 @default.
• W2069483518 hasConcept C2780261241 @default.
• W2069483518 hasConcept C39519442 @default.
• W2069483518 hasConcept C43617362 @default.
• W2069483518 hasConcept C71924100 @default.
• W2069483518 hasConcept C97355855 @default.
• W2069483518 hasConceptScore W2069483518C113196181 @default.
• W2069483518 hasConceptScore W2069483518C121332964 @default.
• W2069483518 hasConceptScore W2069483518C126322002 @default.
• W2069483518 hasConceptScore W2069483518C147789679 @default.
• W2069483518 hasConceptScore W2069483518C178790620 @default.
• W2069483518 hasConceptScore W2069483518C185592680 @default.
• W2069483518 hasConceptScore W2069483518C187530423 @default.
• W2069483518 hasConceptScore W2069483518C192562407 @default.
• W2069483518 hasConceptScore W2069483518C199289684 @default.
• W2069483518 hasConceptScore W2069483518C2776042228 @default.
• W2069483518 hasConceptScore W2069483518C2777419714 @default.
• W2069483518 hasConceptScore W2069483518C2778724459 @default.
• W2069483518 hasConceptScore W2069483518C2779345167 @default.
• W2069483518 hasConceptScore W2069483518C2780261241 @default.
• W2069483518 hasConceptScore W2069483518C39519442 @default.
• W2069483518 hasConceptScore W2069483518C43617362 @default.
• W2069483518 hasConceptScore W2069483518C71924100 @default.
• W2069483518 hasConceptScore W2069483518C97355855 @default.
• W2069483518 hasIssue "8" @default.
• W2069483518 hasLocation W20694835181 @default.

• next