Matches in SemOpenAlex for { <https://semopenalex.org/work/W2069485748> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2069485748 endingPage "1219" @default.
- W2069485748 startingPage "1214" @default.
- W2069485748 abstract "<h3>Objective</h3> To evaluate the effect of amantadine on corneal endothelial cells in subjects with Parkinson's disease. <h3>Design</h3> Cross-sectional study. <h3>Participants</h3> A total of 169 subjects (169 eyes) taking amantadine orally for Parkinson's disease and the same number of age- and gender-matched controls. <h3>Methods</h3> Endothelial indices were compared between the amantadine-treated and age-matched control groups. The amantadine-treated group was divided into 3 subgroups according to the cumulative dose and duration of treatment. Endothelial changes were compared between the amantadine group and the normal control group, and among subgroups. <h3>Main Outcome Measures</h3> Slit-lamp biomicroscopy, central corneal thickness (CCT), endothelial cell density (ECD), coefficient of variation, and hexagonality. <h3>Results</h3> The amantadine group had significantly lower ECD (mean ± standard error; 2662.47±29.06 vs. 2784.72±25.89, <i>P</i> = 0.002), lower hexagonality (56.94±1.07 vs. 60.97±0.87, <i>P</i> = 0.004), and greater coefficient of variation (35.59±0.57 vs. 32.66±0.52, <i>P</i> = 0.000) compared with the age-matched control group. Longer duration and higher cumulative dose amantadine therapy led to a greater reduction in ECD (<i>P</i><0.05) compared with the normal age-matched control group. <h3>Conclusions</h3> Amantadine is more likely to have an effect on corneal endothelial cells in a dose-dependent manner when used long-term. <h3>Financial Disclosure(s)</h3> The author(s) have no proprietary or commercial interest in any materials discussed in this article." @default.
- W2069485748 created "2016-06-24" @default.
- W2069485748 creator A5014806693 @default.
- W2069485748 creator A5044698881 @default.
- W2069485748 creator A5048095375 @default.
- W2069485748 creator A5063319696 @default.
- W2069485748 creator A5074651367 @default.
- W2069485748 creator A5085452750 @default.
- W2069485748 date "2010-06-01" @default.
- W2069485748 modified "2023-10-18" @default.
- W2069485748 title "The Effect of Amantadine on Corneal Endothelium in Subjects with Parkinson's Disease" @default.
- W2069485748 cites W127787013 @default.
- W2069485748 cites W1970137802 @default.
- W2069485748 cites W1976967052 @default.
- W2069485748 cites W1985456422 @default.
- W2069485748 cites W2000816858 @default.
- W2069485748 cites W2007037518 @default.
- W2069485748 cites W2017580746 @default.
- W2069485748 cites W2042948438 @default.
- W2069485748 cites W2048155502 @default.
- W2069485748 cites W2048369284 @default.
- W2069485748 cites W2054621952 @default.
- W2069485748 cites W2058331936 @default.
- W2069485748 cites W2064372503 @default.
- W2069485748 cites W2066902664 @default.
- W2069485748 cites W2131818788 @default.
- W2069485748 cites W2154315436 @default.
- W2069485748 cites W4255884851 @default.
- W2069485748 doi "https://doi.org/10.1016/j.ophtha.2009.10.039" @default.
- W2069485748 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20153901" @default.
- W2069485748 hasPublicationYear "2010" @default.
- W2069485748 type Work @default.
- W2069485748 sameAs 2069485748 @default.
- W2069485748 citedByCount "30" @default.
- W2069485748 countsByYear W20694857482012 @default.
- W2069485748 countsByYear W20694857482013 @default.
- W2069485748 countsByYear W20694857482014 @default.
- W2069485748 countsByYear W20694857482015 @default.
- W2069485748 countsByYear W20694857482016 @default.
- W2069485748 countsByYear W20694857482017 @default.
- W2069485748 countsByYear W20694857482018 @default.
- W2069485748 countsByYear W20694857482019 @default.
- W2069485748 countsByYear W20694857482020 @default.
- W2069485748 countsByYear W20694857482021 @default.
- W2069485748 countsByYear W20694857482022 @default.
- W2069485748 countsByYear W20694857482023 @default.
- W2069485748 crossrefType "journal-article" @default.
- W2069485748 hasAuthorship W2069485748A5014806693 @default.
- W2069485748 hasAuthorship W2069485748A5044698881 @default.
- W2069485748 hasAuthorship W2069485748A5048095375 @default.
- W2069485748 hasAuthorship W2069485748A5063319696 @default.
- W2069485748 hasAuthorship W2069485748A5074651367 @default.
- W2069485748 hasAuthorship W2069485748A5085452750 @default.
- W2069485748 hasBestOaLocation W20694857481 @default.
- W2069485748 hasConcept C118487528 @default.
- W2069485748 hasConcept C126322002 @default.
- W2069485748 hasConcept C164705383 @default.
- W2069485748 hasConcept C2776992346 @default.
- W2069485748 hasConcept C2777374534 @default.
- W2069485748 hasConcept C2779134260 @default.
- W2069485748 hasConcept C2779734285 @default.
- W2069485748 hasConcept C71924100 @default.
- W2069485748 hasConcept C98274493 @default.
- W2069485748 hasConceptScore W2069485748C118487528 @default.
- W2069485748 hasConceptScore W2069485748C126322002 @default.
- W2069485748 hasConceptScore W2069485748C164705383 @default.
- W2069485748 hasConceptScore W2069485748C2776992346 @default.
- W2069485748 hasConceptScore W2069485748C2777374534 @default.
- W2069485748 hasConceptScore W2069485748C2779134260 @default.
- W2069485748 hasConceptScore W2069485748C2779734285 @default.
- W2069485748 hasConceptScore W2069485748C71924100 @default.
- W2069485748 hasConceptScore W2069485748C98274493 @default.
- W2069485748 hasIssue "6" @default.
- W2069485748 hasLocation W20694857481 @default.
- W2069485748 hasLocation W20694857482 @default.
- W2069485748 hasOpenAccess W2069485748 @default.
- W2069485748 hasPrimaryLocation W20694857481 @default.
- W2069485748 hasRelatedWork W2011347913 @default.
- W2069485748 hasRelatedWork W2049397185 @default.
- W2069485748 hasRelatedWork W2074833529 @default.
- W2069485748 hasRelatedWork W2159512267 @default.
- W2069485748 hasRelatedWork W2304633692 @default.
- W2069485748 hasRelatedWork W2399063111 @default.
- W2069485748 hasRelatedWork W2419014549 @default.
- W2069485748 hasRelatedWork W3141700921 @default.
- W2069485748 hasRelatedWork W4212888446 @default.
- W2069485748 hasRelatedWork W4293308774 @default.
- W2069485748 hasVolume "117" @default.
- W2069485748 isParatext "false" @default.
- W2069485748 isRetracted "false" @default.
- W2069485748 magId "2069485748" @default.
- W2069485748 workType "article" @default.