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• W2069496768 abstract "On the basis of data showing a bimodal distribution of values for extracellular pH (pHe), and a discontinuous delta PCO2/delta lactate relationship, Kraig et al. (1986) proposed that H+ is grossly compartmentalized between neurons and glia in the ischemic brain. We measured delta pHe during ischemia, varying ischemic lactate contents between 9 and 38 mmol kg-1. No bimodal distribution was found, but delta pHe varied linearly with lactate content. Because we have also failed to record a discontinuous delta PCO2/delta lactate relationship, we conclude that major compartmentation of H+ does not occur during ischemia." @default.
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• W2069496768 date "1991-07-01" @default.
• W2069496768 modified "2023-10-14" @default.
• W2069496768 title "Extracellular pH in the Brain during Ischemia: Relationship to the Severity of Lactic Acidosis" @default.
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• W2069496768 doi "https://doi.org/10.1038/jcbfm.1991.109" @default.
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