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- W2069500521 abstract "American biochemist and pharmacologist Julius Axelrod shared the 1970 Nobel Prize in physiology or medicine with two physiologists, British Sir Bernard Katz (1911-) and Swedish Ulf Svante von Euler (1905–1983). The citation was as follows: “for their discoveries concerning the humoral transmitters in the nerve terminals and the mechanism for their storage, release, and inactivation.” Axelrod's specific contribution was identifying an enzyme that degrades chemical neurotransmitters within the nervous system after they are no longer needed to transmit nerve impulses. He discovered that norepinephrine could be neutralized by an enzyme, catechol-O-methyltransferase, which he isolated and named. The enzyme proved critical to the understanding of the nervous system and is useful in dealing with the effects of certain psychotropic drugs and in research on hypertension and schizophrenia." @default.
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- W2069500521 date "1994-02-01" @default.
- W2069500521 modified "2023-09-26" @default.
- W2069500521 title "Julius Axelrod—American Biochemist and Nobel Prize Winner" @default.
- W2069500521 doi "https://doi.org/10.1016/s0025-6196(12)61039-8" @default.
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