Matches in SemOpenAlex for { <https://semopenalex.org/work/W2069537082> ?p ?o ?g. }
- W2069537082 endingPage "532" @default.
- W2069537082 startingPage "522" @default.
- W2069537082 abstract "Abstract Micropatterning of hydrogels is potentially useful for a variety of applications, including tissue engineering, fundamental biological studies, diagnostics, and high‐throughput screening. Although synthetic polymers have been developed for these applications, natural polymers such as polysaccharides may have advantages for biological samples and cell‐based devices because they are natural components of the in vivo microenvironment. In this study, we synthesized and used hyaluronic acid (HA) modified with photoreactive methacrylates to fabricate microstructures as functional components of microfabricated devices. To demonstrate the universality of this approach, two types of microstructures were formed. In the first approach, HA microstructures were fabricated and used as docking templates to enable the subsequent formation of cell microarrays within low shear stress regions of the patterns. Cells within these microwells remained viable, could generate spheroids, and could be retrieved using mechanical disruption. In the second approach, cells were encapsulated directly within the HA hydrogels. Arrays of viable embryonic stem (ES) cells or fibroblasts were encapsulated within HA hydrogels and could later be recovered using enzymatic digestion of the microstructures. These results demonstrate that it is possible to incorporate photocrosslinkable HA, a natural, versatile, degradable, and biocompatible biopolymer, into micro‐electromechanical systems. © 2006 Wiley Periodicals, Inc. J Biomed Mater Res, 2006" @default.
- W2069537082 created "2016-06-24" @default.
- W2069537082 creator A5002990376 @default.
- W2069537082 creator A5003288721 @default.
- W2069537082 creator A5006751278 @default.
- W2069537082 creator A5026268740 @default.
- W2069537082 creator A5033056518 @default.
- W2069537082 creator A5041195708 @default.
- W2069537082 creator A5042597057 @default.
- W2069537082 date "2006-06-20" @default.
- W2069537082 modified "2023-10-10" @default.
- W2069537082 title "Micromolding of photocrosslinkable hyaluronic acid for cell encapsulation and entrapment" @default.
- W2069537082 cites W1698518057 @default.
- W2069537082 cites W1966962106 @default.
- W2069537082 cites W1982372103 @default.
- W2069537082 cites W1983352401 @default.
- W2069537082 cites W1987671596 @default.
- W2069537082 cites W1988775440 @default.
- W2069537082 cites W1989199493 @default.
- W2069537082 cites W1991816095 @default.
- W2069537082 cites W1995829317 @default.
- W2069537082 cites W2001308282 @default.
- W2069537082 cites W2003330618 @default.
- W2069537082 cites W2010229362 @default.
- W2069537082 cites W2010446343 @default.
- W2069537082 cites W2010846389 @default.
- W2069537082 cites W2013827506 @default.
- W2069537082 cites W2021592954 @default.
- W2069537082 cites W2022689478 @default.
- W2069537082 cites W2022836746 @default.
- W2069537082 cites W2023313908 @default.
- W2069537082 cites W2024422582 @default.
- W2069537082 cites W2034100579 @default.
- W2069537082 cites W2039382734 @default.
- W2069537082 cites W2043938126 @default.
- W2069537082 cites W2047134067 @default.
- W2069537082 cites W2051069490 @default.
- W2069537082 cites W2051920559 @default.
- W2069537082 cites W2052098523 @default.
- W2069537082 cites W2052675507 @default.
- W2069537082 cites W2058096164 @default.
- W2069537082 cites W2058242764 @default.
- W2069537082 cites W2059075807 @default.
- W2069537082 cites W2063422118 @default.
- W2069537082 cites W2066772900 @default.
- W2069537082 cites W2069120999 @default.
- W2069537082 cites W2070190764 @default.
- W2069537082 cites W2071628173 @default.
- W2069537082 cites W2074139312 @default.
- W2069537082 cites W2081121706 @default.
- W2069537082 cites W2083160182 @default.
- W2069537082 cites W2119708685 @default.
- W2069537082 cites W2121484578 @default.
- W2069537082 cites W2136899344 @default.
- W2069537082 cites W2137034111 @default.
- W2069537082 cites W2149482213 @default.
- W2069537082 cites W2164527416 @default.
- W2069537082 cites W2169391121 @default.
- W2069537082 doi "https://doi.org/10.1002/jbm.a.30821" @default.
- W2069537082 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16788972" @default.
- W2069537082 hasPublicationYear "2006" @default.
- W2069537082 type Work @default.
- W2069537082 sameAs 2069537082 @default.
- W2069537082 citedByCount "208" @default.
- W2069537082 countsByYear W20695370822012 @default.
- W2069537082 countsByYear W20695370822013 @default.
- W2069537082 countsByYear W20695370822014 @default.
- W2069537082 countsByYear W20695370822015 @default.
- W2069537082 countsByYear W20695370822016 @default.
- W2069537082 countsByYear W20695370822017 @default.
- W2069537082 countsByYear W20695370822018 @default.
- W2069537082 countsByYear W20695370822019 @default.
- W2069537082 countsByYear W20695370822020 @default.
- W2069537082 countsByYear W20695370822021 @default.
- W2069537082 countsByYear W20695370822022 @default.
- W2069537082 countsByYear W20695370822023 @default.
- W2069537082 crossrefType "journal-article" @default.
- W2069537082 hasAuthorship W2069537082A5002990376 @default.
- W2069537082 hasAuthorship W2069537082A5003288721 @default.
- W2069537082 hasAuthorship W2069537082A5006751278 @default.
- W2069537082 hasAuthorship W2069537082A5026268740 @default.
- W2069537082 hasAuthorship W2069537082A5033056518 @default.
- W2069537082 hasAuthorship W2069537082A5041195708 @default.
- W2069537082 hasAuthorship W2069537082A5042597057 @default.
- W2069537082 hasConcept C108586683 @default.
- W2069537082 hasConcept C1318750 @default.
- W2069537082 hasConcept C136229726 @default.
- W2069537082 hasConcept C159985019 @default.
- W2069537082 hasConcept C171250308 @default.
- W2069537082 hasConcept C171874014 @default.
- W2069537082 hasConcept C188027245 @default.
- W2069537082 hasConcept C192562407 @default.
- W2069537082 hasConcept C193855658 @default.
- W2069537082 hasConcept C2777529286 @default.
- W2069537082 hasConcept C2778636629 @default.
- W2069537082 hasConcept C2780609957 @default.
- W2069537082 hasConcept C2859760 @default.
- W2069537082 hasConcept C2909316542 @default.