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- W2069675631 abstract "Ninety-one clinical isolates of Staphylococcus aureus have been tested with the Kirby Bauer and the Etest® method to determine the susceptibility to glycopeptides in the 2007–2010 period. Five strains (5·5%) were resistant to vancomycin and nine (9·9%) to teicoplanin. Teicoplanin showed a median minimal inhibitory concentration (MIC) of 1 mg/l (range 0·125–24 mg/l), an MIC50 of 1 mg/l, and an MIC90 of 2 mg/l; vancomycin had a median MIC of 1·5 mg/l (range 0·38–4 mg/l), an MIC50 of 1·5 mg/l, and an MIC90 of 2 mg/l. More isolates were distributed on higher values of MIC for vancomycin. Inhibition halos induced by vancomycin-impregnated paper diskettes were slightly larger than those by teicoplanin. Glycopeptide resistance among methicillin-resistant Staphylococcus aureus in Italy is an underestimated phenomenon, possibly due to the described underestimation of glycopeptides MICs by the automatic broth microdilution method, when compared to agar MIC assays. A teicoplanin MIC creep, as reported for vancomycin, cannot be assumed." @default.
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- W2069675631 date "2012-08-01" @default.
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- W2069675631 title "Comparison of teicoplanin and vancomycin<i>in vitro</i>activity on clinical isolates of<i>Staphylococcus aureus</i>" @default.
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- W2069675631 doi "https://doi.org/10.1179/1973947812y.0000000026" @default.
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