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- W2069694633 abstract "Leupeptin (N-acetyl-L-leucyl-L-leucyl-L-argininal) was produced as an extracellular metabolite by Streptomyces lavendulae. Addition of lysine to the growth medium stimulated leupeptin production from 200 to 1400 micrograms/ml. Incubation of late exponential phase mycelium in a synthetic medium was used to prepare single labelled (3H) and double labelled (3H/14C) inhibitor for metabolic studies. An improved purification scheme that generates leupeptin of high purity with good recoveries is also reported." @default.
- W2069694633 created "2016-06-24" @default.
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- W2069694633 date "1986-01-01" @default.
- W2069694633 modified "2023-09-27" @default.
- W2069694633 title "Preparation and purification of the proteinase inhibitor, leupeptin, from culture filtrates of Streptomyces lavendulae" @default.
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- W2069694633 doi "https://doi.org/10.1016/0020-711x(86)90058-3" @default.
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