Matches in SemOpenAlex for { <https://semopenalex.org/work/W2069726995> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2069726995 endingPage "70" @default.
- W2069726995 startingPage "66" @default.
- W2069726995 abstract "Purpose of the review Anemia is associated with increased perioperative morbidity and mortality, especially in patients with cardiovascular disease. Although blood transfusions are commonly used in these patients, there is little evidence that such an approach improved patients' clinical outcome. Recent findings From an experimental point of view, tolerance to acute anemia is significantly reduced in animals with externally applied coronary artery stenosis. In rats subjected to transient coronary occlusion, however, moderate isovolemic hemodilution attenuated myocardial damage and improved survival. Tolerance to severe anemia could also be improved by hyperoxic ventilation and maintenance of adequate coronary perfusion pressure. From the clinical perspective, tolerance to anemia in patients with cardiovascular disease closely depends on myocardial oxygen demand, in particular on the level of heart rate. A reduction in heart rate as observed in anesthetized patients undergoing moderate hemodilution may confer some cardioprotection. Summary The absolute lowest threshold for anemia in patients with cardiac disease cannot be established. Further studies are needed to develop evidence-based transfusion guidelines for these patients. Rather than primarily focusing on transfusion, physicians should first administer therapies that have been shown to improve outcome. In the setting of coronary artery disease, control of heart rate appears of paramount importance." @default.
- W2069726995 created "2016-06-24" @default.
- W2069726995 creator A5014049215 @default.
- W2069726995 creator A5027287788 @default.
- W2069726995 date "2008-02-01" @default.
- W2069726995 modified "2023-10-03" @default.
- W2069726995 title "Hemodilution and anemia in patients with cardiac disease: what is the safe limit?" @default.
- W2069726995 cites W1834897345 @default.
- W2069726995 cites W1965461705 @default.
- W2069726995 cites W1972669243 @default.
- W2069726995 cites W1976201501 @default.
- W2069726995 cites W1982577232 @default.
- W2069726995 cites W1983939797 @default.
- W2069726995 cites W1986294961 @default.
- W2069726995 cites W1994883270 @default.
- W2069726995 cites W1997419342 @default.
- W2069726995 cites W1998640784 @default.
- W2069726995 cites W1999613101 @default.
- W2069726995 cites W2009056326 @default.
- W2069726995 cites W2015401609 @default.
- W2069726995 cites W2019777747 @default.
- W2069726995 cites W2020218579 @default.
- W2069726995 cites W2032633359 @default.
- W2069726995 cites W2038774050 @default.
- W2069726995 cites W2042916763 @default.
- W2069726995 cites W2048471256 @default.
- W2069726995 cites W2053881283 @default.
- W2069726995 cites W2054591315 @default.
- W2069726995 cites W2055192813 @default.
- W2069726995 cites W2061045750 @default.
- W2069726995 cites W2061903475 @default.
- W2069726995 cites W2072426474 @default.
- W2069726995 cites W2073161599 @default.
- W2069726995 cites W2077710671 @default.
- W2069726995 cites W2085296221 @default.
- W2069726995 cites W2085306418 @default.
- W2069726995 cites W2096750760 @default.
- W2069726995 cites W2097239054 @default.
- W2069726995 cites W2100009404 @default.
- W2069726995 cites W2109973294 @default.
- W2069726995 cites W2127110326 @default.
- W2069726995 cites W2127963725 @default.
- W2069726995 cites W2129346421 @default.
- W2069726995 cites W2132694135 @default.
- W2069726995 cites W2142838862 @default.
- W2069726995 cites W2154783291 @default.
- W2069726995 cites W2167654729 @default.
- W2069726995 cites W4297194585 @default.
- W2069726995 doi "https://doi.org/10.1097/aco.0b013e3282f35ebf" @default.
- W2069726995 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18195613" @default.
- W2069726995 hasPublicationYear "2008" @default.
- W2069726995 type Work @default.
- W2069726995 sameAs 2069726995 @default.
- W2069726995 citedByCount "9" @default.
- W2069726995 countsByYear W20697269952012 @default.
- W2069726995 countsByYear W20697269952013 @default.
- W2069726995 countsByYear W20697269952014 @default.
- W2069726995 countsByYear W20697269952015 @default.
- W2069726995 countsByYear W20697269952018 @default.
- W2069726995 crossrefType "journal-article" @default.
- W2069726995 hasAuthorship W2069726995A5014049215 @default.
- W2069726995 hasAuthorship W2069726995A5027287788 @default.
- W2069726995 hasConcept C126322002 @default.
- W2069726995 hasConcept C164705383 @default.
- W2069726995 hasConcept C177713679 @default.
- W2069726995 hasConcept C2778213512 @default.
- W2069726995 hasConcept C2778248108 @default.
- W2069726995 hasConcept C31174226 @default.
- W2069726995 hasConcept C42219234 @default.
- W2069726995 hasConcept C71924100 @default.
- W2069726995 hasConceptScore W2069726995C126322002 @default.
- W2069726995 hasConceptScore W2069726995C164705383 @default.
- W2069726995 hasConceptScore W2069726995C177713679 @default.
- W2069726995 hasConceptScore W2069726995C2778213512 @default.
- W2069726995 hasConceptScore W2069726995C2778248108 @default.
- W2069726995 hasConceptScore W2069726995C31174226 @default.
- W2069726995 hasConceptScore W2069726995C42219234 @default.
- W2069726995 hasConceptScore W2069726995C71924100 @default.
- W2069726995 hasIssue "1" @default.
- W2069726995 hasLocation W20697269951 @default.
- W2069726995 hasLocation W20697269952 @default.
- W2069726995 hasOpenAccess W2069726995 @default.
- W2069726995 hasPrimaryLocation W20697269951 @default.
- W2069726995 hasRelatedWork W2352247659 @default.
- W2069726995 hasRelatedWork W2354785620 @default.
- W2069726995 hasRelatedWork W2375359181 @default.
- W2069726995 hasRelatedWork W2392422383 @default.
- W2069726995 hasRelatedWork W2586998360 @default.
- W2069726995 hasRelatedWork W2767618185 @default.
- W2069726995 hasRelatedWork W2993789966 @default.
- W2069726995 hasRelatedWork W4319770546 @default.
- W2069726995 hasRelatedWork W4324096639 @default.
- W2069726995 hasRelatedWork W3006168697 @default.
- W2069726995 hasVolume "21" @default.
- W2069726995 isParatext "false" @default.
- W2069726995 isRetracted "false" @default.
- W2069726995 magId "2069726995" @default.
- W2069726995 workType "article" @default.