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- W2069759343 abstract "Hypothalamic 5′-adenosine monophosphate-activated protein kinase (AMPK) senses intracellular metabolic stress, i.e., an increase in the cellular AMP:ATP ratio, and integrates diverse hormonal and nutritional signals to restore energy balance. Recent evidence suggests that different nutrients can modulate AMPK activity in the hypothalamus, thereby controlling weight gain through a leptin-independent mechanism. Understanding the mechanisms by which nutrients control hypothalamic AMPK activity is crucial to the development of effective nutritional interventions for the treatment of food intake-related disorders, such as anorexia and obesity. This article highlights the current evidence for the intricate relationship between nutrients and hypothalamic AMPK activity." @default.
- W2069759343 created "2016-06-24" @default.
- W2069759343 creator A5035784002 @default.
- W2069759343 creator A5055351360 @default.
- W2069759343 creator A5066508537 @default.
- W2069759343 creator A5091119942 @default.
- W2069759343 date "2013-02-01" @default.
- W2069759343 modified "2023-10-18" @default.
- W2069759343 title "The role of neuronal AMPK as a mediator of nutritional regulation of food intake and energy homeostasis" @default.
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