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- W2069773476 abstract "The in vitro effect of acrylamide and its analogues on rat brain glycolytic enzymes was examined to elucidate the biochemical lesions responsible for the pathogenesis of acrylamide-induced neuropathy. All test compounds inhibited glyceraldehyde-3-phosphate dehydrogenase, irrespective of their neurotoxicity, and their inhibitory potency was a linear function of the rate constant with reduced glutathione. Phosphofructokinase was also inhibited by some of the test compounds, independently of their neurotoxicity. The rate-limiting enzymes in glycolysis, hexokinase and pyruvate kinase, were not inhibited by acrylamide." @default.
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- W2069773476 title "Effect of acrylamide and related compounds on glycolytic enzymes of rat brain" @default.
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- W2069773476 doi "https://doi.org/10.1016/0378-4274(85)90188-2" @default.
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