FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2069793722> ?p ?o ?g. }

• W2069793722 endingPage "154" @default.
• W2069793722 startingPage "149" @default.
• W2069793722 abstract "Inhaled corticosteroids remain the most important therapy for chronic asthma in both adults and children. As all inhaled corticosteroids act by binding to a common glucocorticoid receptor there is little evidence of any real difference in clinical efficacy between the different inhaled corticosteroids. The main potential differences are in their propensity to cause side effects. Local side effects such as a hoarse voice do occur in a proportion of adults and there is some limited evidence that ciclesonide may cause less local side effects. In adults there is little evidence for clinically important systemic side effects from doses of inhaled steroids below 800 mcg/day (beclomethasone equivalent). Above this dose a proportion of patients may show some adrenocortical suppression, though it is unlikely to be of clinical importance. Data on bone mineral density and fracture rates is discrepant, but an overview would suggest that below 800 mcg/day there is no increase in fracture risk whereas above this dose there might be an increased fracture risk. The properties of ciclesonide would suggest that it has less propensity for systemic side effects, but large long-term studies are needed to confirm this. In children using inhaled steroids at above-licensed doses reductions in short-term growth can occur, but there is little evidence for reductions in long-term growth at normal doses. At above-licensed doses, biochemical adrenocortical suppression can occur with some unusual but documented cases of clinical Addisonian crisis. Limited evidence in paediatric age groups would suggest that ciclesonide may have some advantage although it is not as yet licensed in all countries for paediatric use. Data on differences in side effects between normal and asthmatic patients, and between asthmatic patients with near-normal lung function compared to those with impaired lung function, indicate that inhaled corticosteroids (particularly fluticasone) are absorbed more in those with normal lung function; this strongly supports stepping down the inhaled steroid dose when asthma is controlled - as is recommended in asthma guidelines." @default.
• W2069793722 created "2016-06-24" @default.
• W2069793722 creator A5008203993 @default.
• W2069793722 date "2007-05-27" @default.
• W2069793722 modified "2023-10-15" @default.
• W2069793722 title "The properties of inhaled corticosteroids: similarities and differences" @default.
• W2069793722 cites W1903824044 @default.
• W2069793722 cites W1939805807 @default.
• W2069793722 cites W1963763550 @default.
• W2069793722 cites W1977761895 @default.
• W2069793722 cites W1982682585 @default.
• W2069793722 cites W1985579704 @default.
• W2069793722 cites W2026566271 @default.
• W2069793722 cites W2044629269 @default.
• W2069793722 cites W2066542174 @default.
• W2069793722 cites W208068470 @default.
• W2069793722 cites W2081059908 @default.
• W2069793722 cites W2094347907 @default.
• W2069793722 cites W2107107374 @default.
• W2069793722 cites W2108069927 @default.
• W2069793722 cites W2110431512 @default.
• W2069793722 cites W2110980418 @default.
• W2069793722 cites W2111225968 @default.
• W2069793722 cites W2115125184 @default.
• W2069793722 cites W2149383913 @default.
• W2069793722 cites W2155830934 @default.
• W2069793722 cites W2160611282 @default.
• W2069793722 cites W2164160360 @default.
• W2069793722 cites W2268275976 @default.
• W2069793722 cites W2322866941 @default.
• W2069793722 cites W2341674111 @default.
• W2069793722 cites W2594805288 @default.
• W2069793722 cites W387031605 @default.
• W2069793722 doi "https://doi.org/10.3132/pcrj.2007.00038" @default.
• W2069793722 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6634205" @default.
• W2069793722 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17530144" @default.
• W2069793722 hasPublicationYear "2007" @default.
• W2069793722 type Work @default.
• W2069793722 sameAs 2069793722 @default.
• W2069793722 citedByCount "71" @default.
• W2069793722 countsByYear W20697937222012 @default.
• W2069793722 countsByYear W20697937222013 @default.
• W2069793722 countsByYear W20697937222014 @default.
• W2069793722 countsByYear W20697937222015 @default.
• W2069793722 countsByYear W20697937222016 @default.
• W2069793722 countsByYear W20697937222018 @default.
• W2069793722 countsByYear W20697937222019 @default.
• W2069793722 countsByYear W20697937222021 @default.
• W2069793722 countsByYear W20697937222022 @default.
• W2069793722 crossrefType "journal-article" @default.
• W2069793722 hasAuthorship W2069793722A5008203993 @default.
• W2069793722 hasBestOaLocation W20697937221 @default.
• W2069793722 hasConcept C126322002 @default.
• W2069793722 hasConcept C199360897 @default.
• W2069793722 hasConcept C2776042228 @default.
• W2069793722 hasConcept C2776954882 @default.
• W2069793722 hasConcept C2777588912 @default.
• W2069793722 hasConcept C2780841215 @default.
• W2069793722 hasConcept C2991922776 @default.
• W2069793722 hasConcept C3454156 @default.
• W2069793722 hasConcept C41008148 @default.
• W2069793722 hasConcept C42219234 @default.
• W2069793722 hasConcept C71924100 @default.
• W2069793722 hasConceptScore W2069793722C126322002 @default.
• W2069793722 hasConceptScore W2069793722C199360897 @default.
• W2069793722 hasConceptScore W2069793722C2776042228 @default.
• W2069793722 hasConceptScore W2069793722C2776954882 @default.
• W2069793722 hasConceptScore W2069793722C2777588912 @default.
• W2069793722 hasConceptScore W2069793722C2780841215 @default.
• W2069793722 hasConceptScore W2069793722C2991922776 @default.
• W2069793722 hasConceptScore W2069793722C3454156 @default.
• W2069793722 hasConceptScore W2069793722C41008148 @default.
• W2069793722 hasConceptScore W2069793722C42219234 @default.
• W2069793722 hasConceptScore W2069793722C71924100 @default.
• W2069793722 hasIssue "3" @default.
• W2069793722 hasLocation W20697937221 @default.
• W2069793722 hasLocation W20697937222 @default.
• W2069793722 hasLocation W20697937223 @default.
• W2069793722 hasLocation W20697937224 @default.
• W2069793722 hasOpenAccess W2069793722 @default.
• W2069793722 hasPrimaryLocation W20697937221 @default.
• W2069793722 hasRelatedWork W1969147007 @default.
• W2069793722 hasRelatedWork W1979797331 @default.
• W2069793722 hasRelatedWork W2058526726 @default.
• W2069793722 hasRelatedWork W2058688302 @default.
• W2069793722 hasRelatedWork W2075414183 @default.
• W2069793722 hasRelatedWork W2357217980 @default.
• W2069793722 hasRelatedWork W2420962679 @default.
• W2069793722 hasRelatedWork W2467530129 @default.
• W2069793722 hasRelatedWork W2574225689 @default.
• W2069793722 hasRelatedWork W2586348017 @default.
• W2069793722 hasVolume "16" @default.
• W2069793722 isParatext "false" @default.
• W2069793722 isRetracted "false" @default.
• W2069793722 magId "2069793722" @default.
• W2069793722 workType "article" @default.