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• W2069794297 abstract "We describe c-Jun, a widely studied transcription factor that participates in cell proliferation, differentiation, and tumorigenesis, as amphitropic. We show that c-Jun forms stable monolayers and interacts favorably, although in a nonselective manner, with phospholipids at the interface. The surface activity of c-Jun, together with that of c-Fos, its common partner in AP-1 transcription heterodimers, drives interfacial complex formation. We show that AP-1 is very stable at the air-water interface and suggest that AP-1 may not be substantially formed in solution as a stable equimolar association of both proteins." @default.
• W2069794297 created "2016-06-24" @default.
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• W2069794297 date "2005-07-01" @default.
• W2069794297 modified "2023-10-09" @default.
• W2069794297 title "c-Jun interacts with phospholipids and c-Fos at the interface" @default.
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• W2069794297 doi "https://doi.org/10.1016/j.jcis.2005.01.069" @default.
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