Matches in SemOpenAlex for { <https://semopenalex.org/work/W2069808516> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2069808516 endingPage "S103" @default.
- W2069808516 startingPage "S103" @default.
- W2069808516 abstract "SM3-O-10 Background: p,p'-DDT (bis[p-chlorophenyl]-1,1,1-trichloroethane) is a persistent organochlorine compound that was used worldwide as an insecticide. Exposure to DDT and DDT metabolites (such as p,p'-DDE) occurs both in utero and through breastfeeding. Given that brain growth continues after birth, both prenatal and postnatal periods are critical windows of vulnerability for the nervous system. DDT has been reported to be neurotoxic in animals, affecting the sodium channels in nerve cell membranes, but little is known about its effects in children. The aim of the study is to evaluate the association of cord serum levels of DDE and DDT with neurodevelopment at age 4. Methods: Two birth cohorts in Ribera d'Ebre and Menorca (Spain) were recruited between 1997 and 1999 (n = 475). Infants were assessed at age 4 using the McCarthy Scales for Infant Development. Organochlorine compounds were measured in cord serum. Children's diet and paternal sociodemographic information was obtained through questionnaire. Results: DDT cord serum concentration at birth was inversely associated with the Verbal, Memory, Quantitative and Perceptual-Performance skills at age 4. Children with DDT concentrations in cord serum above 0.20 ng/mL had a mean decrease of 7.86 (SE = 3.21) points in the verbal scale and a mean decrease of 10.86 (SE = 4.33) points in the memory scale when compared with those with concentrations below 0.05 ng/mL. These associations were stronger among girls. Conclusions: Prenatal exposure to background low-level concentrations of DDT was associated with a decrease in the cognitive skills among preschoolers. These results should be considered when evaluating the risk and benefits of spraying DDT in antimalarial and other disease-vector campaigns." @default.
- W2069808516 created "2016-06-24" @default.
- W2069808516 creator A5006633701 @default.
- W2069808516 creator A5006882369 @default.
- W2069808516 creator A5010557376 @default.
- W2069808516 creator A5013242463 @default.
- W2069808516 creator A5033274362 @default.
- W2069808516 creator A5046359435 @default.
- W2069808516 creator A5060323529 @default.
- W2069808516 date "2006-11-01" @default.
- W2069808516 modified "2023-10-16" @default.
- W2069808516 title "In Utero Exposure to Background Concentrations of DDT and Cognitive Functioning Among Preschoolers" @default.
- W2069808516 doi "https://doi.org/10.1097/00001648-200611001-00250" @default.
- W2069808516 hasPublicationYear "2006" @default.
- W2069808516 type Work @default.
- W2069808516 sameAs 2069808516 @default.
- W2069808516 citedByCount "0" @default.
- W2069808516 crossrefType "journal-article" @default.
- W2069808516 hasAuthorship W2069808516A5006633701 @default.
- W2069808516 hasAuthorship W2069808516A5006882369 @default.
- W2069808516 hasAuthorship W2069808516A5010557376 @default.
- W2069808516 hasAuthorship W2069808516A5013242463 @default.
- W2069808516 hasAuthorship W2069808516A5033274362 @default.
- W2069808516 hasAuthorship W2069808516A5046359435 @default.
- W2069808516 hasAuthorship W2069808516A5060323529 @default.
- W2069808516 hasBestOaLocation W20698085161 @default.
- W2069808516 hasConcept C172680121 @default.
- W2069808516 hasConcept C187212893 @default.
- W2069808516 hasConcept C201614185 @default.
- W2069808516 hasConcept C2776283161 @default.
- W2069808516 hasConcept C2779234561 @default.
- W2069808516 hasConcept C3018923374 @default.
- W2069808516 hasConcept C42407357 @default.
- W2069808516 hasConcept C46973012 @default.
- W2069808516 hasConcept C54355233 @default.
- W2069808516 hasConcept C71924100 @default.
- W2069808516 hasConcept C86803240 @default.
- W2069808516 hasConceptScore W2069808516C172680121 @default.
- W2069808516 hasConceptScore W2069808516C187212893 @default.
- W2069808516 hasConceptScore W2069808516C201614185 @default.
- W2069808516 hasConceptScore W2069808516C2776283161 @default.
- W2069808516 hasConceptScore W2069808516C2779234561 @default.
- W2069808516 hasConceptScore W2069808516C3018923374 @default.
- W2069808516 hasConceptScore W2069808516C42407357 @default.
- W2069808516 hasConceptScore W2069808516C46973012 @default.
- W2069808516 hasConceptScore W2069808516C54355233 @default.
- W2069808516 hasConceptScore W2069808516C71924100 @default.
- W2069808516 hasConceptScore W2069808516C86803240 @default.
- W2069808516 hasIssue "Suppl" @default.
- W2069808516 hasLocation W20698085161 @default.
- W2069808516 hasLocation W20698085162 @default.
- W2069808516 hasOpenAccess W2069808516 @default.
- W2069808516 hasPrimaryLocation W20698085161 @default.
- W2069808516 hasRelatedWork W1483078653 @default.
- W2069808516 hasRelatedWork W2001843739 @default.
- W2069808516 hasRelatedWork W2001854410 @default.
- W2069808516 hasRelatedWork W2006813420 @default.
- W2069808516 hasRelatedWork W2047002590 @default.
- W2069808516 hasRelatedWork W2140513498 @default.
- W2069808516 hasRelatedWork W2397299030 @default.
- W2069808516 hasRelatedWork W2416042392 @default.
- W2069808516 hasRelatedWork W3023069117 @default.
- W2069808516 hasRelatedWork W91425569 @default.
- W2069808516 hasVolume "17" @default.
- W2069808516 isParatext "false" @default.
- W2069808516 isRetracted "false" @default.
- W2069808516 magId "2069808516" @default.
- W2069808516 workType "article" @default.