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- W2069822948 abstract "Significance Demands of modern society force many work operations into the night, when the intrinsic circadian timing system promotes sleep. Overnight shiftwork is associated with increased risk for adverse metabolic health and sleep disruption. Uncovering potential physiological mechanisms that contribute to metabolic dysregulation when work and eating occur at inappropriate circadian times is vital to the development of effective treatment strategies. In this study, healthy volunteers underwent a commonly used simulated shiftwork protocol to quantify changes in metabolic, sleep, and circadian physiology when working and eating during the night as compared with a traditional day work schedule. We demonstrate that nightshift work reduces total daily energy expenditure, representing a contributing mechanism for unwanted weight gain and obesity." @default.
- W2069822948 created "2016-06-24" @default.
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- W2069822948 date "2014-11-17" @default.
- W2069822948 modified "2023-10-15" @default.
- W2069822948 title "Impact of circadian misalignment on energy metabolism during simulated nightshift work" @default.
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- W2069822948 doi "https://doi.org/10.1073/pnas.1412021111" @default.
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