FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2069840290> ?p ?o ?g. }

• W2069840290 endingPage "36" @default.
• W2069840290 startingPage "31" @default.
• W2069840290 abstract "To evaluate the efficacy and tolerance of capecitabine (CAP) given every other week and biweekly oxaliplatin (OX; modified CAPOX regimen) in patients with advanced colorectal cancer previously treated with irinote- can-based frontline chemotherapy.Sixty-seven patients were enrolled; the median age was 62 years and 62 (92.5%) had a performance status (ECOG) of 0-1. OX and CAP were administered at the dose of 100 mg/m(2) on day 1 and 2,000 mg/m(2) on days 1-7, respectively, every 2 weeks.A total of 429 treatment cycles were administered. Grade 3/4 neutropenia and thrombocytopenia were observed in 4 (6%) and 2 (3%) patients, respectively. Febrile neutropenia complicated 1 treatment cycle. The main nonhematologic toxicities were grade 2/3 peripheral sensory neurotoxicity (10% of patients) and grade 3/4 diarrhea (7%). In an intention-to-treat analysis, 3 (4.5%) complete and 13 (19.4%) partial responses (overall response rate 24%) were observed. Seventeen (24.5%) patients had stable and 27 (40.3%) progressive disease. The median time to tumor progression and overall survival were 5 months and 11.3 months, respectively.The results indicate that the modified CAPOX regimen is safe and effective as salvage treatment in patients with advanced colorectal cancer who were previously treated with irinotecan-based frontline therapy." @default.
• W2069840290 created "2016-06-24" @default.
• W2069840290 creator A5002334565 @default.
• W2069840290 creator A5009113561 @default.
• W2069840290 creator A5019893325 @default.
• W2069840290 creator A5038502241 @default.
• W2069840290 creator A5040090394 @default.
• W2069840290 creator A5042177139 @default.
• W2069840290 creator A5043849331 @default.
• W2069840290 creator A5054375277 @default.
• W2069840290 creator A5076032623 @default.
• W2069840290 creator A5077410158 @default.
• W2069840290 creator A5078192662 @default.
• W2069840290 creator A5087834972 @default.
• W2069840290 date "2008-01-01" @default.
• W2069840290 modified "2023-09-26" @default.
• W2069840290 title "Modified CAPOX (Capecitabine plus Oxaliplatin) Regimen Every Two Weeks as Second-Line Treatment in Patients with Advanced Colorectal Cancer Previously Treated with Irinotecan-Based Frontline Therapy" @default.
• W2069840290 cites W1837306378 @default.
• W2069840290 cites W1837926236 @default.
• W2069840290 cites W1910716144 @default.
• W2069840290 cites W1919810009 @default.
• W2069840290 cites W1995684282 @default.
• W2069840290 cites W2014637687 @default.
• W2069840290 cites W2032553799 @default.
• W2069840290 cites W2044970916 @default.
• W2069840290 cites W2052457410 @default.
• W2069840290 cites W2085328261 @default.
• W2069840290 cites W2104689857 @default.
• W2069840290 cites W2113919377 @default.
• W2069840290 cites W2139248078 @default.
• W2069840290 cites W2155421004 @default.
• W2069840290 cites W2171829291 @default.
• W2069840290 cites W2285157229 @default.
• W2069840290 cites W2404129597 @default.
• W2069840290 cites W2409911594 @default.
• W2069840290 doi "https://doi.org/10.1159/000138977" @default.
• W2069840290 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18544957" @default.
• W2069840290 hasPublicationYear "2008" @default.
• W2069840290 type Work @default.
• W2069840290 sameAs 2069840290 @default.
• W2069840290 citedByCount "4" @default.
• W2069840290 countsByYear W20698402902013 @default.
• W2069840290 countsByYear W20698402902014 @default.
• W2069840290 countsByYear W20698402902015 @default.
• W2069840290 countsByYear W20698402902021 @default.
• W2069840290 crossrefType "journal-article" @default.
• W2069840290 hasAuthorship W2069840290A5002334565 @default.
• W2069840290 hasAuthorship W2069840290A5009113561 @default.
• W2069840290 hasAuthorship W2069840290A5019893325 @default.
• W2069840290 hasAuthorship W2069840290A5038502241 @default.
• W2069840290 hasAuthorship W2069840290A5040090394 @default.
• W2069840290 hasAuthorship W2069840290A5042177139 @default.
• W2069840290 hasAuthorship W2069840290A5043849331 @default.
• W2069840290 hasAuthorship W2069840290A5054375277 @default.
• W2069840290 hasAuthorship W2069840290A5076032623 @default.
• W2069840290 hasAuthorship W2069840290A5077410158 @default.
• W2069840290 hasAuthorship W2069840290A5078192662 @default.
• W2069840290 hasAuthorship W2069840290A5087834972 @default.
• W2069840290 hasConcept C121608353 @default.
• W2069840290 hasConcept C126322002 @default.
• W2069840290 hasConcept C141071460 @default.
• W2069840290 hasConcept C2776694085 @default.
• W2069840290 hasConcept C2777063308 @default.
• W2069840290 hasConcept C2777909004 @default.
• W2069840290 hasConcept C2778336483 @default.
• W2069840290 hasConcept C2778822529 @default.
• W2069840290 hasConcept C2780259306 @default.
• W2069840290 hasConcept C2780962732 @default.
• W2069840290 hasConcept C2781413609 @default.
• W2069840290 hasConcept C526805850 @default.
• W2069840290 hasConcept C71924100 @default.
• W2069840290 hasConcept C90924648 @default.
• W2069840290 hasConceptScore W2069840290C121608353 @default.
• W2069840290 hasConceptScore W2069840290C126322002 @default.
• W2069840290 hasConceptScore W2069840290C141071460 @default.
• W2069840290 hasConceptScore W2069840290C2776694085 @default.
• W2069840290 hasConceptScore W2069840290C2777063308 @default.
• W2069840290 hasConceptScore W2069840290C2777909004 @default.
• W2069840290 hasConceptScore W2069840290C2778336483 @default.
• W2069840290 hasConceptScore W2069840290C2778822529 @default.
• W2069840290 hasConceptScore W2069840290C2780259306 @default.
• W2069840290 hasConceptScore W2069840290C2780962732 @default.
• W2069840290 hasConceptScore W2069840290C2781413609 @default.
• W2069840290 hasConceptScore W2069840290C526805850 @default.
• W2069840290 hasConceptScore W2069840290C71924100 @default.
• W2069840290 hasConceptScore W2069840290C90924648 @default.
• W2069840290 hasIssue "1-2" @default.
• W2069840290 hasLocation W20698402901 @default.
• W2069840290 hasLocation W20698402902 @default.
• W2069840290 hasOpenAccess W2069840290 @default.
• W2069840290 hasPrimaryLocation W20698402901 @default.
• W2069840290 hasRelatedWork W1876680356 @default.
• W2069840290 hasRelatedWork W1985460050 @default.
• W2069840290 hasRelatedWork W1990994894 @default.
• W2069840290 hasRelatedWork W2097042400 @default.
• W2069840290 hasRelatedWork W2146230542 @default.
• W2069840290 hasRelatedWork W2358087495 @default.
• W2069840290 hasRelatedWork W2366982708 @default.

• next