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• W2069853528 abstract "A randomised, modified, double-blind trial was conducted in children 2 to <5 years of age to evaluate immunogenicity and reactogenicity of a meningococcal (serogroups A, C, Y, W135) diphtheria toxoid conjugate vaccine (MCV-4) in healthy children previously vaccinated with a monovalent meningococcal C conjugate vaccine. Participants received one dose of either MCV-4 or Haemophilus influenzae type b vaccine (Hib vaccine, control group). Serum bactericidal antibodies (SBA) were determined in sera obtained before and approximately 28 days following vaccination. MCV-4 was highly immunogenic for serogroups A, C, Y and W135, the response to serogroup C being consistent with a booster response in participants primed with monovalent C conjugate vaccine. No major between-group differences in solicited local and systemic reactions or adverse events (AEs)." @default.
• W2069853528 created "2016-06-24" @default.
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• W2069853528 date "2006-03-24" @default.
• W2069853528 modified "2023-09-27" @default.
• W2069853528 title "Antibody responses to meningococcal (groups A, C, Y and W135) polysaccharide diphtheria toxoid conjugate vaccine in children who previously received meningococcal C conjugate vaccine" @default.
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• W2069853528 doi "https://doi.org/10.1016/j.vaccine.2005.12.018" @default.
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