FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2069866366> ?p ?o ?g. }

• W2069866366 endingPage "548" @default.
• W2069866366 startingPage "543" @default.
• W2069866366 abstract "Background: Urinary tract infections (UTI) are common in children and contribute significantly to morbidity and mortality. The major cause is Escherichia coli, carrying multiple virulence-associated factors (VFs). However, the specific traits that distinguish childhood uropathogenic E. coli from fecal commensals of healthy children are incompletely defined. Methods: We used a multiplex polymerase chain reaction–based reverse line blot assay, several additional polymerase chain reactions and phenotypic methods to compare distributions of virulence traits (22 VF genes, UTI-associated O types, phylogenetic groups, sequence type 131 and expression of selected VFs), between 212 E. coli isolates from children ≤5 years with UTI (109 cystitis and 103 pyelonephritis) and 115 fecal isolates from healthy children of similar age, collected during the same time period. Results: The studied traits were most prevalent among pyelonephritis, followed closely by cystitis isolates and were uncommon among fecal isolates. Eight VF genes differentiated pyelonephritis from cystitis isolates, but aggregate VF scores in these 2 UTI groups were similar. Most of the studied phenotypic characteristics showed a similar descending prevalence gradient from pyelonephritis, through cystitis, to fecal isolates. Coexpression of biofilm components, curli and cellulose, was strongly associated with pyelonephritis, phylogenetic group B2, individual VF genes and higher VF scores. Two-thirds (67%) of clinical isolates belonged to phylogenetic group B2 and, of these, 12% belonged to the sequence type 131 clonal group, compared with 14% and 1%, respectively, of fecal isolates. Conclusions: These findings identify specific virulence factors, O types and a virulent clonal group (sequence type 131), as potential targets for UTI prevention strategies in children." @default.
• W2069866366 created "2016-06-24" @default.
• W2069866366 creator A5021576126 @default.
• W2069866366 creator A5034386514 @default.
• W2069866366 creator A5043105198 @default.
• W2069866366 creator A5055204011 @default.
• W2069866366 creator A5080782442 @default.
• W2069866366 creator A5090899683 @default.
• W2069866366 date "2013-05-01" @default.
• W2069866366 modified "2023-09-26" @default.
• W2069866366 title "Genotypic and Phenotypic Characterization of Escherichia coli Isolates From Children With Urinary Tract Infection and From Healthy Carriers" @default.
• W2069866366 cites W1857808857 @default.
• W2069866366 cites W1970540449 @default.
• W2069866366 cites W1976732885 @default.
• W2069866366 cites W1990731735 @default.
• W2069866366 cites W1994246342 @default.
• W2069866366 cites W2002648188 @default.
• W2069866366 cites W2009482512 @default.
• W2069866366 cites W2014298338 @default.
• W2069866366 cites W2038667562 @default.
• W2069866366 cites W2046008552 @default.
• W2069866366 cites W2056929310 @default.
• W2069866366 cites W2059141881 @default.
• W2069866366 cites W2061593388 @default.
• W2069866366 cites W2073699143 @default.
• W2069866366 cites W2076065428 @default.
• W2069866366 cites W2082988422 @default.
• W2069866366 cites W2086538363 @default.
• W2069866366 cites W2093527665 @default.
• W2069866366 cites W2093906324 @default.
• W2069866366 cites W2094167392 @default.
• W2069866366 cites W2100775251 @default.
• W2069866366 cites W2104926496 @default.
• W2069866366 cites W2111216098 @default.
• W2069866366 cites W2121444381 @default.
• W2069866366 cites W2125201618 @default.
• W2069866366 cites W2126990727 @default.
• W2069866366 cites W2131056415 @default.
• W2069866366 cites W2136429020 @default.
• W2069866366 cites W2141858020 @default.
• W2069866366 cites W2150412000 @default.
• W2069866366 cites W2151301449 @default.
• W2069866366 cites W2152155545 @default.
• W2069866366 cites W2158682148 @default.
• W2069866366 cites W2163298956 @default.
• W2069866366 cites W2170639356 @default.
• W2069866366 cites W3184858568 @default.
• W2069866366 doi "https://doi.org/10.1097/inf.0b013e31828ba3f1" @default.
• W2069866366 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23429563" @default.
• W2069866366 hasPublicationYear "2013" @default.
• W2069866366 type Work @default.
• W2069866366 sameAs 2069866366 @default.
• W2069866366 citedByCount "34" @default.
• W2069866366 countsByYear W20698663662013 @default.
• W2069866366 countsByYear W20698663662014 @default.
• W2069866366 countsByYear W20698663662015 @default.
• W2069866366 countsByYear W20698663662016 @default.
• W2069866366 countsByYear W20698663662017 @default.
• W2069866366 countsByYear W20698663662018 @default.
• W2069866366 countsByYear W20698663662019 @default.
• W2069866366 countsByYear W20698663662020 @default.
• W2069866366 crossrefType "journal-article" @default.
• W2069866366 hasAuthorship W2069866366A5021576126 @default.
• W2069866366 hasAuthorship W2069866366A5034386514 @default.
• W2069866366 hasAuthorship W2069866366A5043105198 @default.
• W2069866366 hasAuthorship W2069866366A5055204011 @default.
• W2069866366 hasAuthorship W2069866366A5080782442 @default.
• W2069866366 hasAuthorship W2069866366A5090899683 @default.
• W2069866366 hasConcept C104317684 @default.
• W2069866366 hasConcept C134018914 @default.
• W2069866366 hasConcept C135763542 @default.
• W2069866366 hasConcept C193252679 @default.
• W2069866366 hasConcept C49105822 @default.
• W2069866366 hasConcept C54355233 @default.
• W2069866366 hasConcept C547475151 @default.
• W2069866366 hasConcept C60987743 @default.
• W2069866366 hasConcept C61716771 @default.
• W2069866366 hasConcept C71924100 @default.
• W2069866366 hasConcept C77411442 @default.
• W2069866366 hasConcept C86803240 @default.
• W2069866366 hasConcept C89423630 @default.
• W2069866366 hasConcept C90583042 @default.
• W2069866366 hasConceptScore W2069866366C104317684 @default.
• W2069866366 hasConceptScore W2069866366C134018914 @default.
• W2069866366 hasConceptScore W2069866366C135763542 @default.
• W2069866366 hasConceptScore W2069866366C193252679 @default.
• W2069866366 hasConceptScore W2069866366C49105822 @default.
• W2069866366 hasConceptScore W2069866366C54355233 @default.
• W2069866366 hasConceptScore W2069866366C547475151 @default.
• W2069866366 hasConceptScore W2069866366C60987743 @default.
• W2069866366 hasConceptScore W2069866366C61716771 @default.
• W2069866366 hasConceptScore W2069866366C71924100 @default.
• W2069866366 hasConceptScore W2069866366C77411442 @default.
• W2069866366 hasConceptScore W2069866366C86803240 @default.
• W2069866366 hasConceptScore W2069866366C89423630 @default.
• W2069866366 hasConceptScore W2069866366C90583042 @default.
• W2069866366 hasIssue "5" @default.
• W2069866366 hasLocation W20698663661 @default.

• next