Matches in SemOpenAlex for { <https://semopenalex.org/work/W2069873417> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2069873417 endingPage "540" @default.
- W2069873417 startingPage "537" @default.
- W2069873417 abstract "It has been observed previously that xanthan gum (XG) and hydroxypropylmethyl cellulose (HPMC) show different drug release behavior. In order to clarify these findings, the rheological properties of both polymers have been determined by oscillatory as well as by steady shear measurements. Aqueous solutions of 4 and 7% (w/w) polymer have been used to simulate the outer surface of a hydrated tablet. The dynamic moduli, i.e., storage modulus (G') and loss modulus (G) of the two polymers have been determined in pure water and USP phosphate buffer pH 7.4 at different dilutions. In this concentration range XG solution exhibits gel-like behavior, while HPMC behaves as a typical polymer solution. These findings are quite consistent with the reported higher ability of XG matrices to retard drug release than HPMC matrices for controlled-release formulation. The effects of differences in drug solubility and acidity, as well as the addition of lactose, and of the ionic strength of the medium on the rheological properties of XG and HPMC solutions have been studied in detail. Among these parameters, only the salt concentration exerts an enhancing effect on both moduli of XG, while no detectable influence on HPMC solution could be observed." @default.
- W2069873417 created "2016-06-24" @default.
- W2069873417 creator A5010623705 @default.
- W2069873417 creator A5033186186 @default.
- W2069873417 creator A5040619932 @default.
- W2069873417 creator A5085883232 @default.
- W2069873417 date "1996-05-01" @default.
- W2069873417 modified "2023-09-27" @default.
- W2069873417 title "Rheological Characterization of Xanthan Gum and Hydroxypropylmethyl Cellulose with Respect to Controlled-Release Drug Delivery" @default.
- W2069873417 cites W173736955 @default.
- W2069873417 cites W1971267409 @default.
- W2069873417 cites W1977861698 @default.
- W2069873417 cites W2006223676 @default.
- W2069873417 cites W2006270969 @default.
- W2069873417 cites W2034296056 @default.
- W2069873417 cites W2046276065 @default.
- W2069873417 cites W2052396402 @default.
- W2069873417 cites W2073786913 @default.
- W2069873417 cites W2085343292 @default.
- W2069873417 cites W2164582044 @default.
- W2069873417 cites W56370387 @default.
- W2069873417 doi "https://doi.org/10.1021/js950476u" @default.
- W2069873417 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8742947" @default.
- W2069873417 hasPublicationYear "1996" @default.
- W2069873417 type Work @default.
- W2069873417 sameAs 2069873417 @default.
- W2069873417 citedByCount "89" @default.
- W2069873417 countsByYear W20698734172012 @default.
- W2069873417 countsByYear W20698734172013 @default.
- W2069873417 countsByYear W20698734172014 @default.
- W2069873417 countsByYear W20698734172015 @default.
- W2069873417 countsByYear W20698734172016 @default.
- W2069873417 countsByYear W20698734172018 @default.
- W2069873417 countsByYear W20698734172019 @default.
- W2069873417 countsByYear W20698734172020 @default.
- W2069873417 countsByYear W20698734172021 @default.
- W2069873417 countsByYear W20698734172022 @default.
- W2069873417 countsByYear W20698734172023 @default.
- W2069873417 crossrefType "journal-article" @default.
- W2069873417 hasAuthorship W2069873417A5010623705 @default.
- W2069873417 hasAuthorship W2069873417A5033186186 @default.
- W2069873417 hasAuthorship W2069873417A5040619932 @default.
- W2069873417 hasAuthorship W2069873417A5085883232 @default.
- W2069873417 hasConcept C127413603 @default.
- W2069873417 hasConcept C155574463 @default.
- W2069873417 hasConcept C159985019 @default.
- W2069873417 hasConcept C178790620 @default.
- W2069873417 hasConcept C184651966 @default.
- W2069873417 hasConcept C185592680 @default.
- W2069873417 hasConcept C192562407 @default.
- W2069873417 hasConcept C200990466 @default.
- W2069873417 hasConcept C2776081644 @default.
- W2069873417 hasConcept C2780100132 @default.
- W2069873417 hasConcept C42360764 @default.
- W2069873417 hasConcept C43617362 @default.
- W2069873417 hasConcept C521977710 @default.
- W2069873417 hasConcept C537181965 @default.
- W2069873417 hasConceptScore W2069873417C127413603 @default.
- W2069873417 hasConceptScore W2069873417C155574463 @default.
- W2069873417 hasConceptScore W2069873417C159985019 @default.
- W2069873417 hasConceptScore W2069873417C178790620 @default.
- W2069873417 hasConceptScore W2069873417C184651966 @default.
- W2069873417 hasConceptScore W2069873417C185592680 @default.
- W2069873417 hasConceptScore W2069873417C192562407 @default.
- W2069873417 hasConceptScore W2069873417C200990466 @default.
- W2069873417 hasConceptScore W2069873417C2776081644 @default.
- W2069873417 hasConceptScore W2069873417C2780100132 @default.
- W2069873417 hasConceptScore W2069873417C42360764 @default.
- W2069873417 hasConceptScore W2069873417C43617362 @default.
- W2069873417 hasConceptScore W2069873417C521977710 @default.
- W2069873417 hasConceptScore W2069873417C537181965 @default.
- W2069873417 hasIssue "5" @default.
- W2069873417 hasLocation W20698734171 @default.
- W2069873417 hasLocation W20698734172 @default.
- W2069873417 hasOpenAccess W2069873417 @default.
- W2069873417 hasPrimaryLocation W20698734171 @default.
- W2069873417 hasRelatedWork W1544745704 @default.
- W2069873417 hasRelatedWork W2013141910 @default.
- W2069873417 hasRelatedWork W2029448303 @default.
- W2069873417 hasRelatedWork W2053035447 @default.
- W2069873417 hasRelatedWork W2075484771 @default.
- W2069873417 hasRelatedWork W3094571986 @default.
- W2069873417 hasRelatedWork W3209407788 @default.
- W2069873417 hasRelatedWork W4206815995 @default.
- W2069873417 hasRelatedWork W4220753920 @default.
- W2069873417 hasRelatedWork W2185093049 @default.
- W2069873417 hasVolume "85" @default.
- W2069873417 isParatext "false" @default.
- W2069873417 isRetracted "false" @default.
- W2069873417 magId "2069873417" @default.
- W2069873417 workType "article" @default.