FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2069883941> ?p ?o ?g. }

• W2069883941 endingPage "297" @default.
• W2069883941 startingPage "291" @default.
• W2069883941 abstract "Purpose of review While it is well established that angiotensin II promotes cardiovascular and renal disorders, recent evidence has indicated a pivotal role in atherosclerotic disease which is distinguished by the central abnormality of lipid accumulation within the vascular wall. Recent findings Studies published in the last year show that angiotensin II activity is increased in atherosclerosis, but even a transient elevation in angiotensin II potentiates the disease. The downstream hormone, aldosterone, has vasculopathic effects in conjunction with, as well as independently of, angiotensin II. The mechanism for angiotensin II injury includes potentiation of damage by known risk factors such as hypertension, hyperlipidemia, diabetes and insulin resistance, falling estrogens and inflammation. In addition, angiotensin II has direct effects on cellular proliferation, hypertrophy, apoptosis, and synthesis/degradation of matrix proteins and collagen that underlie development and progression of atherosclerosis as well as stability of the plaque. Antagonism of angiotensin II actions, therefore, offers the possibility of interfering with these direct and indirect effects and lessening the progression of atherosclerosis, stabilizing vulnerable plaques, and even reversing the disease. Summary Angiotensin is increased in atherosclerosis, and increased angiotensin II amplifies atherosclerosis by modulating individual risk factors as well as by directly affecting lipid metabolism, the vascular response to lipid accumulation, and plaque stability. Antagonism of angiotensin II actions not only lessens the progression of atherosclerosis, but stabilizes the plaque and may even cause regression of the disease." @default.
• W2069883941 created "2016-06-24" @default.
• W2069883941 creator A5033940069 @default.
• W2069883941 creator A5087255918 @default.
• W2069883941 date "2004-05-01" @default.
• W2069883941 modified "2023-10-17" @default.
• W2069883941 title "Angiotensin in atherosclerosis" @default.
• W2069883941 cites W1497388823 @default.
• W2069883941 cites W1592471891 @default.
• W2069883941 cites W1604542334 @default.
• W2069883941 cites W180946569 @default.
• W2069883941 cites W1889421242 @default.
• W2069883941 cites W1910105482 @default.
• W2069883941 cites W1974047732 @default.
• W2069883941 cites W1982920623 @default.
• W2069883941 cites W1983323298 @default.
• W2069883941 cites W1994915655 @default.
• W2069883941 cites W1999819607 @default.
• W2069883941 cites W2006353464 @default.
• W2069883941 cites W2008478163 @default.
• W2069883941 cites W2009001954 @default.
• W2069883941 cites W2014952428 @default.
• W2069883941 cites W2026540628 @default.
• W2069883941 cites W2033240204 @default.
• W2069883941 cites W2034914625 @default.
• W2069883941 cites W2042984581 @default.
• W2069883941 cites W2043600435 @default.
• W2069883941 cites W2051242048 @default.
• W2069883941 cites W2053634523 @default.
• W2069883941 cites W2064099037 @default.
• W2069883941 cites W2072085494 @default.
• W2069883941 cites W2074375778 @default.
• W2069883941 cites W2080214882 @default.
• W2069883941 cites W2083073587 @default.
• W2069883941 cites W2086060574 @default.
• W2069883941 cites W2088609718 @default.
• W2069883941 cites W2089900480 @default.
• W2069883941 cites W2090024638 @default.
• W2069883941 cites W2090362677 @default.
• W2069883941 cites W2093875985 @default.
• W2069883941 cites W2095507444 @default.
• W2069883941 cites W2095762368 @default.
• W2069883941 cites W2096372312 @default.
• W2069883941 cites W2098780362 @default.
• W2069883941 cites W2098796887 @default.
• W2069883941 cites W2104340865 @default.
• W2069883941 cites W2108095879 @default.
• W2069883941 cites W2108988373 @default.
• W2069883941 cites W2109690433 @default.
• W2069883941 cites W2111116814 @default.
• W2069883941 cites W2113259481 @default.
• W2069883941 cites W2113273743 @default.
• W2069883941 cites W2114722474 @default.
• W2069883941 cites W2116458615 @default.
• W2069883941 cites W2116968443 @default.
• W2069883941 cites W2120978344 @default.
• W2069883941 cites W2121061143 @default.
• W2069883941 cites W2122740041 @default.
• W2069883941 cites W2128334034 @default.
• W2069883941 cites W2130146234 @default.
• W2069883941 cites W2130501592 @default.
• W2069883941 cites W2131702141 @default.
• W2069883941 cites W2133217116 @default.
• W2069883941 cites W2135642402 @default.
• W2069883941 cites W2136714451 @default.
• W2069883941 cites W2139360228 @default.
• W2069883941 cites W2149408586 @default.
• W2069883941 cites W2159220813 @default.
• W2069883941 cites W2161271210 @default.
• W2069883941 cites W2163768086 @default.
• W2069883941 cites W2171655301 @default.
• W2069883941 cites W2312400976 @default.
• W2069883941 cites W2315001920 @default.
• W2069883941 cites W2319810263 @default.
• W2069883941 cites W2322394974 @default.
• W2069883941 cites W2562329777 @default.
• W2069883941 cites W2615684303 @default.
• W2069883941 cites W2034413061 @default.
• W2069883941 doi "https://doi.org/10.1097/00041552-200405000-00005" @default.
• W2069883941 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15073487" @default.
• W2069883941 hasPublicationYear "2004" @default.
• W2069883941 type Work @default.
• W2069883941 sameAs 2069883941 @default.
• W2069883941 citedByCount "38" @default.
• W2069883941 countsByYear W20698839412013 @default.
• W2069883941 countsByYear W20698839412020 @default.
• W2069883941 countsByYear W20698839412022 @default.
• W2069883941 countsByYear W20698839412023 @default.
• W2069883941 crossrefType "journal-article" @default.
• W2069883941 hasAuthorship W2069883941A5033940069 @default.
• W2069883941 hasAuthorship W2069883941A5087255918 @default.
• W2069883941 hasConcept C123915805 @default.
• W2069883941 hasConcept C126322002 @default.
• W2069883941 hasConcept C134018914 @default.
• W2069883941 hasConcept C198710026 @default.
• W2069883941 hasConcept C2779091943 @default.
• W2069883941 hasConcept C2908929049 @default.
• W2069883941 hasConcept C555293320 @default.

• next