Matches in SemOpenAlex for { <https://semopenalex.org/work/W2069884490> ?p ?o ?g. }
- W2069884490 endingPage "439" @default.
- W2069884490 startingPage "431" @default.
- W2069884490 abstract "Although intraspousal transmission of hepatitis C virus (HCV) has been speculated, there is no direct evidence.To investigate whether transmission of HCV occurs by this route, 295 spouses of persons diagnosed with HCV were studied. Of these, 25 (8.8%) tested positive for anti-HCV. Next, the HCV genotype was determined by polymerase chain reaction using a mixed primer set, and cDNA was obtained in 17 of the 25 couples for comparison of the genotypes.Of these 17, 14 (82.4%) spouses were shown to be infected with HCV of the same genotype. Analysis of the nucleotide sequences of putative E1 gene of eight couples having the same HCV genotype revealed that five couples had remarkably high nucleotide sequence homologies (> 97%), whereas samples obtained from the remaining three couples showed relatively low homology (91-92%). Nucleotide sequence homologies were significantly higher between spouses than between non-spouse pairs of isolates. Phylogenetic analysis using the neighbor-joining method suggests that infection in these five couples probably occurred after marriage. Furthermore, none of the five couples had shared other possible transmission routes such as intravenous drug use, dental treatment or acupuncture.These data strongly suggest the occurrence of intraspousal transmission of HCV." @default.
- W2069884490 created "2016-06-24" @default.
- W2069884490 creator A5015577892 @default.
- W2069884490 creator A5023958825 @default.
- W2069884490 creator A5031710130 @default.
- W2069884490 creator A5037620642 @default.
- W2069884490 creator A5044932403 @default.
- W2069884490 creator A5066429603 @default.
- W2069884490 creator A5071497400 @default.
- W2069884490 creator A5086743926 @default.
- W2069884490 date "1995-04-01" @default.
- W2069884490 modified "2023-10-11" @default.
- W2069884490 title "Molecular analysis of intraspousal transmission of hepatitis C virus" @default.
- W2069884490 cites W1581048386 @default.
- W2069884490 cites W1721893764 @default.
- W2069884490 cites W1971792395 @default.
- W2069884490 cites W1974879228 @default.
- W2069884490 cites W1974952301 @default.
- W2069884490 cites W1982780078 @default.
- W2069884490 cites W1983264742 @default.
- W2069884490 cites W1988055498 @default.
- W2069884490 cites W1988153645 @default.
- W2069884490 cites W1989098951 @default.
- W2069884490 cites W1992003142 @default.
- W2069884490 cites W1999487724 @default.
- W2069884490 cites W2001241073 @default.
- W2069884490 cites W2001713235 @default.
- W2069884490 cites W2006309458 @default.
- W2069884490 cites W2022053117 @default.
- W2069884490 cites W2030040190 @default.
- W2069884490 cites W2033098004 @default.
- W2069884490 cites W2034570206 @default.
- W2069884490 cites W2035254749 @default.
- W2069884490 cites W2038449539 @default.
- W2069884490 cites W2047480444 @default.
- W2069884490 cites W2055031628 @default.
- W2069884490 cites W2057749731 @default.
- W2069884490 cites W2060858410 @default.
- W2069884490 cites W2062174742 @default.
- W2069884490 cites W2066124462 @default.
- W2069884490 cites W2067060571 @default.
- W2069884490 cites W2069250521 @default.
- W2069884490 cites W2070474258 @default.
- W2069884490 cites W2073903623 @default.
- W2069884490 cites W2076265592 @default.
- W2069884490 cites W2077980272 @default.
- W2069884490 cites W2084424046 @default.
- W2069884490 cites W2089302400 @default.
- W2069884490 cites W2095116196 @default.
- W2069884490 cites W2097970363 @default.
- W2069884490 cites W2110309669 @default.
- W2069884490 cites W2114725097 @default.
- W2069884490 cites W2124528668 @default.
- W2069884490 cites W2124917202 @default.
- W2069884490 cites W2126365434 @default.
- W2069884490 cites W2137718170 @default.
- W2069884490 cites W2138270253 @default.
- W2069884490 cites W2150482242 @default.
- W2069884490 cites W2151764231 @default.
- W2069884490 cites W2152766761 @default.
- W2069884490 cites W2168297506 @default.
- W2069884490 cites W2324876068 @default.
- W2069884490 cites W2328171401 @default.
- W2069884490 cites W4229955267 @default.
- W2069884490 doi "https://doi.org/10.1016/0168-8278(95)80106-5" @default.
- W2069884490 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7665861" @default.
- W2069884490 hasPublicationYear "1995" @default.
- W2069884490 type Work @default.
- W2069884490 sameAs 2069884490 @default.
- W2069884490 citedByCount "86" @default.
- W2069884490 countsByYear W20698844902012 @default.
- W2069884490 countsByYear W20698844902013 @default.
- W2069884490 countsByYear W20698844902014 @default.
- W2069884490 countsByYear W20698844902015 @default.
- W2069884490 countsByYear W20698844902016 @default.
- W2069884490 countsByYear W20698844902017 @default.
- W2069884490 countsByYear W20698844902019 @default.
- W2069884490 crossrefType "journal-article" @default.
- W2069884490 hasAuthorship W2069884490A5015577892 @default.
- W2069884490 hasAuthorship W2069884490A5023958825 @default.
- W2069884490 hasAuthorship W2069884490A5031710130 @default.
- W2069884490 hasAuthorship W2069884490A5037620642 @default.
- W2069884490 hasAuthorship W2069884490A5044932403 @default.
- W2069884490 hasAuthorship W2069884490A5066429603 @default.
- W2069884490 hasAuthorship W2069884490A5071497400 @default.
- W2069884490 hasAuthorship W2069884490A5086743926 @default.
- W2069884490 hasConcept C104317684 @default.
- W2069884490 hasConcept C119599485 @default.
- W2069884490 hasConcept C127413603 @default.
- W2069884490 hasConcept C135763542 @default.
- W2069884490 hasConcept C159047783 @default.
- W2069884490 hasConcept C165525559 @default.
- W2069884490 hasConcept C178790620 @default.
- W2069884490 hasConcept C185592680 @default.
- W2069884490 hasConcept C187882448 @default.
- W2069884490 hasConcept C193252679 @default.
- W2069884490 hasConcept C2522874641 @default.
- W2069884490 hasConcept C2776408679 @default.