FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2069892761> ?p ?o ?g. }

• W2069892761 endingPage "91" @default.
• W2069892761 startingPage "86" @default.
• W2069892761 abstract "Visuospatial skills including spatial navigation are known to be impaired in Huntington's disease. Spatial navigation comprises two navigational frameworks, allocentric and egocentric. Several studies have associated the allocentric navigation with the hippocampus and the egocentric navigation with the striatum. The striatum is predominantly impaired from the early stages of Huntington's disease.To find whether spatial navigation impairment is present in the early stages of Huntington's disease and to test the hypothesis that the egocentric navigation is predominantly affected compared to the allocentric navigation.In nineteen patients with Huntington's disease the egocentric and the allocentric navigation skills were tested using the Blue Velvet Arena, a human analog of Morris Water Maze, and compared to nineteen age and gender-matched healthy controls. Cognitive functions, with emphasis on the executive functions, were also assessed.The spatial navigation skills deteriorated with the increasing motor impairment in Huntington's disease. These changes only became apparent in patients with moderate functional impairment. No difference between the egocentric and the allocentric skills was seen.Spatial navigation deficit is not an early marker of the cognitive dysfunction in Huntington's disease. We speculate that the striatal circuitry that is known to degenerate early in the course of Huntington's disease is not directly associated with the spatial navigation." @default.
• W2069892761 created "2016-06-24" @default.
• W2069892761 creator A5015434498 @default.
• W2069892761 creator A5025814190 @default.
• W2069892761 creator A5048521509 @default.
• W2069892761 creator A5064895122 @default.
• W2069892761 creator A5068403567 @default.
• W2069892761 creator A5080845172 @default.
• W2069892761 creator A5082174276 @default.
• W2069892761 creator A5091253870 @default.
• W2069892761 date "2012-01-01" @default.
• W2069892761 modified "2023-10-12" @default.
• W2069892761 title "Disturbance of real space navigation in moderately advanced but not in early Huntington's disease" @default.
• W2069892761 cites W1540528271 @default.
• W2069892761 cites W1964132438 @default.
• W2069892761 cites W1964150594 @default.
• W2069892761 cites W1964469142 @default.
• W2069892761 cites W1964666126 @default.
• W2069892761 cites W1970006557 @default.
• W2069892761 cites W1970732501 @default.
• W2069892761 cites W1973433476 @default.
• W2069892761 cites W1978989899 @default.
• W2069892761 cites W1980497105 @default.
• W2069892761 cites W1994059999 @default.
• W2069892761 cites W1995119071 @default.
• W2069892761 cites W1997994621 @default.
• W2069892761 cites W2000214310 @default.
• W2069892761 cites W2007442485 @default.
• W2069892761 cites W2014617249 @default.
• W2069892761 cites W2017169966 @default.
• W2069892761 cites W2034544906 @default.
• W2069892761 cites W2036731732 @default.
• W2069892761 cites W2038984813 @default.
• W2069892761 cites W2055962836 @default.
• W2069892761 cites W2056916404 @default.
• W2069892761 cites W2062102056 @default.
• W2069892761 cites W2062364641 @default.
• W2069892761 cites W2063654543 @default.
• W2069892761 cites W2078904697 @default.
• W2069892761 cites W2079835282 @default.
• W2069892761 cites W2082056883 @default.
• W2069892761 cites W2082446434 @default.
• W2069892761 cites W2084841026 @default.
• W2069892761 cites W2086996808 @default.
• W2069892761 cites W2095002870 @default.
• W2069892761 cites W2104600915 @default.
• W2069892761 cites W2112765259 @default.
• W2069892761 cites W2117341801 @default.
• W2069892761 cites W2132732050 @default.
• W2069892761 cites W2135204629 @default.
• W2069892761 cites W2138884364 @default.
• W2069892761 cites W2162532664 @default.
• W2069892761 cites W2163001824 @default.
• W2069892761 cites W2167740291 @default.
• W2069892761 cites W4206144694 @default.
• W2069892761 cites W4251038643 @default.
• W2069892761 doi "https://doi.org/10.1016/j.jns.2011.08.016" @default.
• W2069892761 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21875725" @default.
• W2069892761 hasPublicationYear "2012" @default.
• W2069892761 type Work @default.
• W2069892761 sameAs 2069892761 @default.
• W2069892761 citedByCount "21" @default.
• W2069892761 countsByYear W20698927612012 @default.
• W2069892761 countsByYear W20698927612013 @default.
• W2069892761 countsByYear W20698927612014 @default.
• W2069892761 countsByYear W20698927612015 @default.
• W2069892761 countsByYear W20698927612016 @default.
• W2069892761 countsByYear W20698927612017 @default.
• W2069892761 countsByYear W20698927612018 @default.
• W2069892761 countsByYear W20698927612019 @default.
• W2069892761 countsByYear W20698927612020 @default.
• W2069892761 countsByYear W20698927612021 @default.
• W2069892761 countsByYear W20698927612022 @default.
• W2069892761 countsByYear W20698927612023 @default.
• W2069892761 crossrefType "journal-article" @default.
• W2069892761 hasAuthorship W2069892761A5015434498 @default.
• W2069892761 hasAuthorship W2069892761A5025814190 @default.
• W2069892761 hasAuthorship W2069892761A5048521509 @default.
• W2069892761 hasAuthorship W2069892761A5064895122 @default.
• W2069892761 hasAuthorship W2069892761A5068403567 @default.
• W2069892761 hasAuthorship W2069892761A5080845172 @default.
• W2069892761 hasAuthorship W2069892761A5082174276 @default.
• W2069892761 hasAuthorship W2069892761A5091253870 @default.
• W2069892761 hasConcept C14216870 @default.
• W2069892761 hasConcept C142724271 @default.
• W2069892761 hasConcept C15744967 @default.
• W2069892761 hasConcept C169760540 @default.
• W2069892761 hasConcept C169900460 @default.
• W2069892761 hasConcept C21963081 @default.
• W2069892761 hasConcept C2775968953 @default.
• W2069892761 hasConcept C2777371692 @default.
• W2069892761 hasConcept C2779134260 @default.
• W2069892761 hasConcept C2779985164 @default.
• W2069892761 hasConcept C2780062018 @default.
• W2069892761 hasConcept C2780647506 @default.
• W2069892761 hasConcept C43729271 @default.
• W2069892761 hasConcept C44752575 @default.
• W2069892761 hasConcept C513476851 @default.

• next