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- W2069896656 abstract "Los acontecimientos adversos respiratorios (AAR) constituyen causas importantes de morbimortalidad postoperatoria. En el presente estudio se investigó la incidencia y los factores determinantes de los AAR postoperatorios. Este estudio prospectivo observacional se llevó a cabo en una unidad de cuidados postanestésicos (UCPA). Se estudió a un total de 340 pacientes adultos ingresados de forma consecutiva, y se evaluaron los AAR después de intervenciones de cirugía programada. Se registraron las características demográficas de la población, los parámetros perioperatorios, la frecuencia de AAR y la duración de la estancia postoperatoria en la UCPA y en el hospital. Los datos se analizaron mediante estadística descriptiva, con la prueba de U de Mann-Whitney y con la prueba de χ2 o la prueba exacta de Fisher. Se realizaron análisis multivariantes con una regresión binaria logística, y se calculó la odds ratio (OR) y su intervalo de confianza (IC) del 95%. Se produjeron AAR postoperatorios en 67 pacientes (19,7%). Los AAR fueron más frecuentes después de intervenciones quirúrgicas de riesgo alto (42% frente a 24%; p = 0,003), en los pacientes a los que se practicaron operaciones de cirugía mayor (37% frente a 25%, p = 0,041), en los que fueron intervenidos bajo anestesia general (85% frente a 67%, p = 0,004) y en los pacientes a los que se administraron relajantes musculares intraoperatorios (79% frente a 55%; p < 0,001) y neostigmina (69% frente a 49%, p = 0,002). Los pacientes con AAR postoperatorios experimentaron con mayor frecuencia una emergencia hipoactiva (13% frente a 5%, p = 0,015) y un bloqueo neuromuscular residual (46% frente a 11%, p < 0,001). En los análisis multivariantes, el bloqueo neuromuscular residual fue un factor de riesgo independiente para la aparición de los AAR en la UCPA (OR 6,4; IC 3,0-13,4; p < 0,001). Los AAR constituyen una complicación postoperatoria importante y frecuente. El bloqueo neuromuscular residual fue un factor de riesgo independiente para la aparición de AAR en la UCPA. Adverse respiratory events (ARE) are a leading causes of postoperative morbidity and mortality. This study investigated the incidence and determinants of postoperative ARE. This observational prospective study was conducted in a post anesthesia care unit (PACU). A total of 340 adult subjects were admitted consecutively, and AREs were measured after elective surgery. Population demographics, perioperative parameters, ARE occurrence, and length of stay in the postoperative PACU and in hospital were recorded. Data were analyzed descriptively using the Mann-Whitney U-test and the Chi-square or Fisher's exact test. Multivariate analyses were carried outusing logistic binary regression, and the odds ratio (OR) and 95% confidence interval (CI) were calculated. Postoperative AREs occurred in 67 subjects (19.7%). AREs were more frequent after high-risk procedures (42% vs 24%; P = .003), in patients undergoing major surgery (37% vs 25%; P = .041), those receiving general anesthesia (85% vs 67%; P = .004), and in patients administered intraoperative muscle relaxants (79% vs 55%; P < .001) and neostigmine (69% vs 49%; P = .002). Hypoactive emergence (13% vs 5%; P = .015) and residual neuromuscular blockade (46% versus 11%; P < .001) were more frequent in subjects with postoperative ARE. On multivariate analyses, residual neuromuscular blockade was an independent risk factor for ARE in the PACU (OR 6.4; CI 3.0-13.4; P < .001). ARE is an important and common postoperative complication. Residual neuromuscular blockade was an independent risk factor for ARE in the PACU." @default.
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- W2069896656 date "2015-02-01" @default.
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- W2069896656 title "Acontecimientos adversos respiratorios en la unidad de cuidados postanestésicos" @default.
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- W2069896656 doi "https://doi.org/10.1016/j.arbres.2014.04.016" @default.
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