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- W2069958319 abstract "Pyrrolobenzodiazepine-diethylphosphonate conjugates have been designed and synthesized that link through two different types of spacers that are simple alkane chain and also a piperazine moiety side-armed with the alkane chains. These pyrrolobenzodiazepine conjugates have exhibited remarkable DNA-binding affinity and improved solubility in water, a representative compound 7d showing promising in vitro cytotoxicity." @default.
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- W2069958319 date "2008-04-01" @default.
- W2069958319 modified "2023-10-11" @default.
- W2069958319 title "Phosphonate-linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates: Synthesis, DNA-binding affinity and cytotoxicity" @default.
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- W2069958319 doi "https://doi.org/10.1016/j.bmc.2008.01.040" @default.
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