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- W2070000215 abstract "<b><i>Background:</i></b> The Psoriasis Area and Severity Index (PASI) is the score of choice to grade psoriasis severity and detect clinical changes. Due to low resolution based on the calculation of the score by fixed area classes, PASI scores <10 have little value. <b><i>Methods:</i></b> At 756 patient examinations, psoriasis activity was measured with both PASI and PrecisePASI. <b><i>Results:</i></b> PrecisePASI has a linear increase while PASI has a staircase pattern. Both scores meet at the endpoint-relevant values of body surface area (BSA) 10, 30, 50, 70 and 90%. PASI and PrecisePASI correlate significantly over the whole range of BSA. In the region of BSA <5%, PrecisePASI shows a significantly higher resolution (p < 0.0001). <b><i>Conclusion:</i></b> The calculation of PrecisePASI corrects the undesired inaccuracies of PASI in the lower BSA ranges and is a tool to use as an endpoint in trials aiming to detect differences in the lower ranges of BSA." @default.
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- W2070000215 date "2015-01-01" @default.
- W2070000215 modified "2023-09-24" @default.
- W2070000215 title "Detection of Small Changes in Psoriasis Intensity with PrecisePASI" @default.
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- W2070000215 doi "https://doi.org/10.1159/000371811" @default.
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