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• W2070036679 abstract "Potent 3,4-disubstituted benzofuran P1' MMP-13 inhibitors have been prepared. Selectivity over MMP-2 was achieved through a substituent at the C4 position of the benzofuran P1' moiety of the molecule. By replacing a backbone benzene with a pyridine and valine with threonine, compounds (e.g., 44) with greatly reduced plasma protein binding were also obtained." @default.
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• W2070036679 date "2009-08-01" @default.
• W2070036679 modified "2023-10-06" @default.
• W2070036679 title "3,4-Disubstituted benzofuran P1′ MMP-13 inhibitors: Optimization of selectivity and reduction of protein binding" @default.
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• W2070036679 doi "https://doi.org/10.1016/j.bmcl.2009.07.008" @default.
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