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- W2070049991 abstract "The effects of thyroxine treatment on body nitrogen, and nitrogen excretion, of adult Rana pipiens were investigated at 18 and 30°C.At 18°C, thyroxine-treated frogs contain more plasma amino nitrogen and less liver and muscle protein than controls; urea excretion is significantly below control levels, but ammonia excretion does not change. Intestinal glycine transport, used as a model for transport and utilization of amino acids in the body, does not change with thyroxine treatment.At 30°C, most results are qualitatively similar to results at 18°C. The exceptions are: thyroxine-treated frogs show significantly reduced glycine absorption; muscle protein nitrogen, and plasma amino nitrogen are not different from control levels.A partial picture of the effects of thyroxine on protein metabolism can be developed. In control animals, protein seems to be utilized as the main source of metabolic energy. In thyroxine-treated frogs, protein mobilization occurs, but cellular permeability to amino acid may decrease. Therefore nitrogen excretion, and perhaps amino acid utilization, decreases. These results are considered in relation to differences in glycogen metabolism and metabolic rate." @default.
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- W2070049991 date "1969-12-01" @default.
- W2070049991 modified "2023-10-18" @default.
- W2070049991 title "The effects of thyroxine on nitrogen metabolism in the Leopard frog, Rana pipiens" @default.
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- W2070049991 doi "https://doi.org/10.1016/0016-6480(69)90266-4" @default.
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