Matches in SemOpenAlex for { <https://semopenalex.org/work/W2070096685> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2070096685 endingPage "431" @default.
- W2070096685 startingPage "425" @default.
- W2070096685 abstract "Esophageal cancer, particularly adenocarcinoma of the esophagus (ACE), has been steadily increasing in incidence in the United States. In the past, patients usually died rapidly with locoregional disease that leads to inanition and aspiration. However, today when patients with ACE are treated successfully with induction chemotherapy and radiation therapy, followed by surgical excision, ACE usually does not recur locally, but presents with metatastic disease. We present a 62-year-old white male with ACE, which was treated with induction chemotherapy and radiation therapy followed by surgical excision. After approximately 1 year with no evidence of locoregional recurrence, the patient presented with diffuse cutaneous metastatic disease.In addition to routine staining immunohistochemical stains for CK(AE1/AE3), CK7, CK 20, EMA, alpha-smooth muscle (SM) actin, S-100 protein, CD34, P53, Bcl-2, c-erbB-2 were performed.The immunohistochemical profile was consistent with an esophageal origin showing positive staining with CK20 and CK7 as well as AE1/AE3 and EMA. In addition, there was marked nuclear expression of p53, as well as membrane expression of c-erb-B2; consistent with progression of the disease and poor response to further cytotoxic therapeutic regimes.With new therapeutic protocols, we can expect to see more metastatic disease with recurrences of ACE. The histopathologic features and the immunohistochemical profile of the recurrent tumors may be helpful in determining alternate forms of therapy that either alone or in combination could be useful in palliation and delaying progression." @default.
- W2070096685 created "2016-06-24" @default.
- W2070096685 creator A5027291613 @default.
- W2070096685 creator A5030534638 @default.
- W2070096685 creator A5034509277 @default.
- W2070096685 date "2001-09-01" @default.
- W2070096685 modified "2023-09-26" @default.
- W2070096685 title "Metastatic adenocarcinoma of the esophagus to the skin: new patterns of tumor recurrence and alternate treatments for palliation" @default.
- W2070096685 cites W1558856267 @default.
- W2070096685 cites W1598952686 @default.
- W2070096685 cites W1971336699 @default.
- W2070096685 cites W1974185882 @default.
- W2070096685 cites W1975675492 @default.
- W2070096685 cites W1979319210 @default.
- W2070096685 cites W1979475097 @default.
- W2070096685 cites W1990050482 @default.
- W2070096685 cites W1999665609 @default.
- W2070096685 cites W2007780460 @default.
- W2070096685 cites W2022921605 @default.
- W2070096685 cites W2031383224 @default.
- W2070096685 cites W2032810655 @default.
- W2070096685 cites W2033791403 @default.
- W2070096685 cites W2040528315 @default.
- W2070096685 cites W2044280607 @default.
- W2070096685 cites W2052815740 @default.
- W2070096685 cites W2058526541 @default.
- W2070096685 cites W2068622871 @default.
- W2070096685 cites W2076229517 @default.
- W2070096685 cites W2077991158 @default.
- W2070096685 cites W2081894694 @default.
- W2070096685 cites W2109549744 @default.
- W2070096685 cites W2112750808 @default.
- W2070096685 cites W2127558096 @default.
- W2070096685 cites W2149987837 @default.
- W2070096685 cites W2168601297 @default.
- W2070096685 cites W2418058082 @default.
- W2070096685 cites W4231986221 @default.
- W2070096685 cites W56887765 @default.
- W2070096685 doi "https://doi.org/10.1034/j.1600-0560.2001.028008425.x" @default.
- W2070096685 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11493381" @default.
- W2070096685 hasPublicationYear "2001" @default.
- W2070096685 type Work @default.
- W2070096685 sameAs 2070096685 @default.
- W2070096685 citedByCount "14" @default.
- W2070096685 countsByYear W20700966852012 @default.
- W2070096685 countsByYear W20700966852013 @default.
- W2070096685 countsByYear W20700966852015 @default.
- W2070096685 countsByYear W20700966852017 @default.
- W2070096685 countsByYear W20700966852021 @default.
- W2070096685 crossrefType "journal-article" @default.
- W2070096685 hasAuthorship W2070096685A5027291613 @default.
- W2070096685 hasAuthorship W2070096685A5030534638 @default.
- W2070096685 hasAuthorship W2070096685A5034509277 @default.
- W2070096685 hasConcept C121608353 @default.
- W2070096685 hasConcept C126322002 @default.
- W2070096685 hasConcept C142724271 @default.
- W2070096685 hasConcept C143998085 @default.
- W2070096685 hasConcept C204232928 @default.
- W2070096685 hasConcept C2776694085 @default.
- W2070096685 hasConcept C2777819096 @default.
- W2070096685 hasConcept C2781182431 @default.
- W2070096685 hasConcept C509974204 @default.
- W2070096685 hasConcept C71924100 @default.
- W2070096685 hasConceptScore W2070096685C121608353 @default.
- W2070096685 hasConceptScore W2070096685C126322002 @default.
- W2070096685 hasConceptScore W2070096685C142724271 @default.
- W2070096685 hasConceptScore W2070096685C143998085 @default.
- W2070096685 hasConceptScore W2070096685C204232928 @default.
- W2070096685 hasConceptScore W2070096685C2776694085 @default.
- W2070096685 hasConceptScore W2070096685C2777819096 @default.
- W2070096685 hasConceptScore W2070096685C2781182431 @default.
- W2070096685 hasConceptScore W2070096685C509974204 @default.
- W2070096685 hasConceptScore W2070096685C71924100 @default.
- W2070096685 hasIssue "8" @default.
- W2070096685 hasLocation W20700966851 @default.
- W2070096685 hasLocation W20700966852 @default.
- W2070096685 hasOpenAccess W2070096685 @default.
- W2070096685 hasPrimaryLocation W20700966851 @default.
- W2070096685 hasRelatedWork W1498202335 @default.
- W2070096685 hasRelatedWork W2014435840 @default.
- W2070096685 hasRelatedWork W2086791042 @default.
- W2070096685 hasRelatedWork W2364854402 @default.
- W2070096685 hasRelatedWork W2364973444 @default.
- W2070096685 hasRelatedWork W2384708512 @default.
- W2070096685 hasRelatedWork W2396366200 @default.
- W2070096685 hasRelatedWork W2404042595 @default.
- W2070096685 hasRelatedWork W2409264417 @default.
- W2070096685 hasRelatedWork W2415717579 @default.
- W2070096685 hasVolume "28" @default.
- W2070096685 isParatext "false" @default.
- W2070096685 isRetracted "false" @default.
- W2070096685 magId "2070096685" @default.
- W2070096685 workType "article" @default.