FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2070129535> ?p ?o ?g. }

• W2070129535 endingPage "303" @default.
• W2070129535 startingPage "296" @default.
• W2070129535 abstract "Dendritic cells (DCs) are pivotal in inducing immunity or alternatively downregulating immune reactivity. In humans, the opposing phenotypic subsets of CD11c+/CD123− “myeloid” DCs and CD123+/CD11c− “lymphoid” DCs have been proposed to orchestrate these immune responses. In this study we determined the absolute numbers of both subsets in three resting hematopoietic tissues by employing a novel flow cytometry method, eliminating processing steps and calculations based on mononuclear cell percentages. Internal bead standards along with the cells of interest were simultaneously acquired directly from unmanipulated whole blood specimens. We found significant differences (p < 0.001) between the mean absolute numbers of CD123+/CD11c− lymphoid DCs among the three sources, with the fewest present in peripheral blood (8.2/μl), about 50% more in cord blood (12.2/μl), and fivefold more in bone marrow (40.2/μl). Cord blood and bone marrow CD11c+/CD123− myeloid DC counts did not differ from each other (23.5/μl and 28.9/μl, respectively) but peripheral blood contained significantly fewer (15.5/μl, p = 0.006). CD11c+/CD123− DCs had significantly higher surface expression of HLA-DR (p < 0.001) in all three sources. To test for association with the DC subsets, T, B, and natural killer (NK) lymphocytes were also enumerated. In bone marrow only, significant correlations were found between the size of the CD123+/CD11c− lymphoid DC pool and NK cells (p = 0.0029) and B cells (p = 0.0033). These data support the hypothesis that a common CD123+/CD11c− DC, NK cell, and B cell progenitor is resident in marrow, and this cell may be identical to the common lymphoid progenitor previously described in mice and/or the human CD34+/Lin−/CD10+ progenitor." @default.
• W2070129535 created "2016-06-24" @default.
• W2070129535 creator A5004502649 @default.
• W2070129535 creator A5015266579 @default.
• W2070129535 creator A5041896298 @default.
• W2070129535 creator A5060384074 @default.
• W2070129535 creator A5062031844 @default.
• W2070129535 creator A5084292285 @default.
• W2070129535 date "2003-05-01" @default.
• W2070129535 modified "2023-09-27" @default.
• W2070129535 title "Absolute Values of Dendritic Cell Subsets in Bone Marrow, Cord Blood, and Peripheral Blood Enumerated by a Novel Method" @default.
• W2070129535 cites W1501513289 @default.
• W2070129535 cites W1661544713 @default.
• W2070129535 cites W1718139154 @default.
• W2070129535 cites W17966201 @default.
• W2070129535 cites W182052287 @default.
• W2070129535 cites W1866642200 @default.
• W2070129535 cites W1935913665 @default.
• W2070129535 cites W1948375327 @default.
• W2070129535 cites W1964282764 @default.
• W2070129535 cites W1975463463 @default.
• W2070129535 cites W1977945339 @default.
• W2070129535 cites W1982860140 @default.
• W2070129535 cites W1997558956 @default.
• W2070129535 cites W1997681881 @default.
• W2070129535 cites W1997708871 @default.
• W2070129535 cites W2012934541 @default.
• W2070129535 cites W2014458327 @default.
• W2070129535 cites W2015954946 @default.
• W2070129535 cites W2019546595 @default.
• W2070129535 cites W2028016355 @default.
• W2070129535 cites W2028092080 @default.
• W2070129535 cites W2037090825 @default.
• W2070129535 cites W2056461632 @default.
• W2070129535 cites W2059059131 @default.
• W2070129535 cites W2059337777 @default.
• W2070129535 cites W2059787743 @default.
• W2070129535 cites W2060405001 @default.
• W2070129535 cites W2062214374 @default.
• W2070129535 cites W2067564880 @default.
• W2070129535 cites W2072926214 @default.
• W2070129535 cites W2072999621 @default.
• W2070129535 cites W2095016279 @default.
• W2070129535 cites W2099149994 @default.
• W2070129535 cites W2108207978 @default.
• W2070129535 cites W2115760138 @default.
• W2070129535 cites W2116147326 @default.
• W2070129535 cites W2116716017 @default.
• W2070129535 cites W2121236896 @default.
• W2070129535 cites W2124376809 @default.
• W2070129535 cites W2131761283 @default.
• W2070129535 cites W2153069489 @default.
• W2070129535 cites W2167366928 @default.
• W2070129535 cites W2170088452 @default.
• W2070129535 cites W2172571745 @default.
• W2070129535 cites W2231583054 @default.
• W2070129535 cites W2322611444 @default.
• W2070129535 cites W2333239721 @default.
• W2070129535 cites W2415234673 @default.
• W2070129535 cites W2418545672 @default.
• W2070129535 cites W4251093572 @default.
• W2070129535 cites W4252805733 @default.
• W2070129535 cites W7493770 @default.
• W2070129535 cites W90568390 @default.
• W2070129535 doi "https://doi.org/10.1634/stemcells.21-3-296" @default.
• W2070129535 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12743324" @default.
• W2070129535 hasPublicationYear "2003" @default.
• W2070129535 type Work @default.
• W2070129535 sameAs 2070129535 @default.
• W2070129535 citedByCount "53" @default.
• W2070129535 countsByYear W20701295352012 @default.
• W2070129535 countsByYear W20701295352013 @default.
• W2070129535 countsByYear W20701295352014 @default.
• W2070129535 countsByYear W20701295352015 @default.
• W2070129535 countsByYear W20701295352018 @default.
• W2070129535 countsByYear W20701295352020 @default.
• W2070129535 countsByYear W20701295352021 @default.
• W2070129535 countsByYear W20701295352022 @default.
• W2070129535 crossrefType "journal-article" @default.
• W2070129535 hasAuthorship W2070129535A5004502649 @default.
• W2070129535 hasAuthorship W2070129535A5015266579 @default.
• W2070129535 hasAuthorship W2070129535A5041896298 @default.
• W2070129535 hasAuthorship W2070129535A5060384074 @default.
• W2070129535 hasAuthorship W2070129535A5062031844 @default.
• W2070129535 hasAuthorship W2070129535A5084292285 @default.
• W2070129535 hasBestOaLocation W20701295351 @default.
• W2070129535 hasConcept C104317684 @default.
• W2070129535 hasConcept C109159458 @default.
• W2070129535 hasConcept C127716648 @default.
• W2070129535 hasConcept C137061746 @default.
• W2070129535 hasConcept C201750760 @default.
• W2070129535 hasConcept C202751555 @default.
• W2070129535 hasConcept C203014093 @default.
• W2070129535 hasConcept C2776090121 @default.
• W2070129535 hasConcept C2778170410 @default.
• W2070129535 hasConcept C2779282312 @default.
• W2070129535 hasConcept C2779919695 @default.
• W2070129535 hasConcept C2780007613 @default.

• next