Matches in SemOpenAlex for { <https://semopenalex.org/work/W2070134315> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2070134315 endingPage "629" @default.
- W2070134315 startingPage "623" @default.
- W2070134315 abstract "Background: Previous studies suggest that chemokines and chemokine receptors have a role in the metastatic process. A correlation exists between the specific expression of these chemoattractive, pro-inflammatory cytokines and the ability of cancer to disseminate. Prior studies have shown that in metastatic melanoma and squamous cell carcinoma of the head and neck upregulation of CXC (α) chemokine receptor (CXCR)4 and CC (β) chemokine receptor (CCR)7 expression is accompanied by downregulation of the chemokine receptor CCR6. However, the expression patterns of CCR6, CCR7 and CXCR4 in non-melanoma skin cancer have yet to be elucidated. Methods: The expression patterns of CCR6, CCR7 and CXCR4 were determined using an immunohistochemical approach on formalin-fixed, paraffin-embedded normal, pre-cancerous actinic (solar) keratosis, squamous cell carcinoma and basal cell carcinoma tissues. Results: Analysis of chemokine receptor expression showed downregulation of CCR6 and upregulation of CCR7 and CXCR4 in potentially metastatic non-melanoma skin cancer, invasive squamous cell carcinoma, but this pattern did not exist in non-melanoma skin cancer with no metastatic potential, basal cell carcinoma; or actinic keratosis, when compared with normal skin. Conclusions: Chemokine receptor expression may influence the biological behavior of non-melanoma skin cancer. The exact mechanism by which this occurs requires further study." @default.
- W2070134315 created "2016-06-24" @default.
- W2070134315 creator A5001648497 @default.
- W2070134315 creator A5014277102 @default.
- W2070134315 creator A5052985668 @default.
- W2070134315 creator A5060850104 @default.
- W2070134315 date "2008-07-01" @default.
- W2070134315 modified "2023-09-23" @default.
- W2070134315 title "Chemokine receptor expression in non-melanoma skin cancer" @default.
- W2070134315 cites W1975197903 @default.
- W2070134315 cites W1983834402 @default.
- W2070134315 cites W1984445615 @default.
- W2070134315 cites W1986986419 @default.
- W2070134315 cites W1994239532 @default.
- W2070134315 cites W2010397777 @default.
- W2070134315 cites W2028509107 @default.
- W2070134315 cites W2065383116 @default.
- W2070134315 cites W2071175338 @default.
- W2070134315 cites W2107560602 @default.
- W2070134315 cites W2115054041 @default.
- W2070134315 cites W2119358637 @default.
- W2070134315 cites W2134605629 @default.
- W2070134315 cites W2141278603 @default.
- W2070134315 cites W2150669332 @default.
- W2070134315 cites W2156323704 @default.
- W2070134315 doi "https://doi.org/10.1111/j.1600-0560.2007.00879.x" @default.
- W2070134315 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18312436" @default.
- W2070134315 hasPublicationYear "2008" @default.
- W2070134315 type Work @default.
- W2070134315 sameAs 2070134315 @default.
- W2070134315 citedByCount "17" @default.
- W2070134315 countsByYear W20701343152013 @default.
- W2070134315 countsByYear W20701343152014 @default.
- W2070134315 countsByYear W20701343152016 @default.
- W2070134315 countsByYear W20701343152017 @default.
- W2070134315 countsByYear W20701343152019 @default.
- W2070134315 countsByYear W20701343152022 @default.
- W2070134315 crossrefType "journal-article" @default.
- W2070134315 hasAuthorship W2070134315A5001648497 @default.
- W2070134315 hasAuthorship W2070134315A5014277102 @default.
- W2070134315 hasAuthorship W2070134315A5052985668 @default.
- W2070134315 hasAuthorship W2070134315A5060850104 @default.
- W2070134315 hasConcept C104317684 @default.
- W2070134315 hasConcept C126322002 @default.
- W2070134315 hasConcept C127561419 @default.
- W2070134315 hasConcept C127801297 @default.
- W2070134315 hasConcept C12823836 @default.
- W2070134315 hasConcept C13373296 @default.
- W2070134315 hasConcept C140944930 @default.
- W2070134315 hasConcept C142724271 @default.
- W2070134315 hasConcept C170493617 @default.
- W2070134315 hasConcept C2777658100 @default.
- W2070134315 hasConcept C2778804307 @default.
- W2070134315 hasConcept C3019992690 @default.
- W2070134315 hasConcept C502942594 @default.
- W2070134315 hasConcept C55493867 @default.
- W2070134315 hasConcept C71924100 @default.
- W2070134315 hasConcept C86803240 @default.
- W2070134315 hasConcept C94205230 @default.
- W2070134315 hasConceptScore W2070134315C104317684 @default.
- W2070134315 hasConceptScore W2070134315C126322002 @default.
- W2070134315 hasConceptScore W2070134315C127561419 @default.
- W2070134315 hasConceptScore W2070134315C127801297 @default.
- W2070134315 hasConceptScore W2070134315C12823836 @default.
- W2070134315 hasConceptScore W2070134315C13373296 @default.
- W2070134315 hasConceptScore W2070134315C140944930 @default.
- W2070134315 hasConceptScore W2070134315C142724271 @default.
- W2070134315 hasConceptScore W2070134315C170493617 @default.
- W2070134315 hasConceptScore W2070134315C2777658100 @default.
- W2070134315 hasConceptScore W2070134315C2778804307 @default.
- W2070134315 hasConceptScore W2070134315C3019992690 @default.
- W2070134315 hasConceptScore W2070134315C502942594 @default.
- W2070134315 hasConceptScore W2070134315C55493867 @default.
- W2070134315 hasConceptScore W2070134315C71924100 @default.
- W2070134315 hasConceptScore W2070134315C86803240 @default.
- W2070134315 hasConceptScore W2070134315C94205230 @default.
- W2070134315 hasIssue "7" @default.
- W2070134315 hasLocation W20701343151 @default.
- W2070134315 hasLocation W20701343152 @default.
- W2070134315 hasOpenAccess W2070134315 @default.
- W2070134315 hasPrimaryLocation W20701343151 @default.
- W2070134315 hasRelatedWork W1512560800 @default.
- W2070134315 hasRelatedWork W1859768551 @default.
- W2070134315 hasRelatedWork W1915016592 @default.
- W2070134315 hasRelatedWork W2015534033 @default.
- W2070134315 hasRelatedWork W2070134315 @default.
- W2070134315 hasRelatedWork W2092305272 @default.
- W2070134315 hasRelatedWork W2315695983 @default.
- W2070134315 hasRelatedWork W2461493830 @default.
- W2070134315 hasRelatedWork W2774044362 @default.
- W2070134315 hasRelatedWork W2788817833 @default.
- W2070134315 hasVolume "35" @default.
- W2070134315 isParatext "false" @default.
- W2070134315 isRetracted "false" @default.
- W2070134315 magId "2070134315" @default.
- W2070134315 workType "article" @default.