Matches in SemOpenAlex for { <https://semopenalex.org/work/W2070135330> ?p ?o ?g. }
- W2070135330 endingPage "1520" @default.
- W2070135330 startingPage "1514" @default.
- W2070135330 abstract "We use atomistic nonequilibrium molecular dynamics simulations to demonstrate how specific ionic flux in peptide nanotubes can be regulated by tailoring the lumen chemistry through single amino acid substitutions. By varying the size and polarity of the functional group inserted into the nanotube interior, we are able to adjust the Na(+) flux by over an order of magnitude. Cl(-) is consistently denied passage. Bulky, nonpolar groups encourage interactions between the Na(+) and the peptide backbone carbonyl groups, disrupting the Na(+) solvation shell and slowing the transport of Na(+). Small groups have the opposite effect and accelerate flow. These results suggest that relative ion flux and selectivity can be precisely regulated in subnanometer pores by molecularly defining the lumen according to biological principles." @default.
- W2070135330 created "2016-06-24" @default.
- W2070135330 creator A5002067531 @default.
- W2070135330 creator A5011370114 @default.
- W2070135330 creator A5014744105 @default.
- W2070135330 creator A5027872356 @default.
- W2070135330 date "2015-04-09" @default.
- W2070135330 modified "2023-09-26" @default.
- W2070135330 title "Regulating Ion Transport in Peptide Nanotubes by Tailoring the Nanotube Lumen Chemistry" @default.
- W2070135330 cites W1963673259 @default.
- W2070135330 cites W1965696184 @default.
- W2070135330 cites W1965775947 @default.
- W2070135330 cites W1966112922 @default.
- W2070135330 cites W1969129798 @default.
- W2070135330 cites W1972758026 @default.
- W2070135330 cites W1976499671 @default.
- W2070135330 cites W1982898268 @default.
- W2070135330 cites W1993190737 @default.
- W2070135330 cites W1993984194 @default.
- W2070135330 cites W1999838269 @default.
- W2070135330 cites W2001979196 @default.
- W2070135330 cites W2012766545 @default.
- W2070135330 cites W2017268899 @default.
- W2070135330 cites W2026632806 @default.
- W2070135330 cites W2026877196 @default.
- W2070135330 cites W2030895914 @default.
- W2070135330 cites W2035687084 @default.
- W2070135330 cites W2052357258 @default.
- W2070135330 cites W2057220321 @default.
- W2070135330 cites W2058064833 @default.
- W2070135330 cites W2059611774 @default.
- W2070135330 cites W2059906178 @default.
- W2070135330 cites W2060433756 @default.
- W2070135330 cites W2060872117 @default.
- W2070135330 cites W2061295544 @default.
- W2070135330 cites W2063660291 @default.
- W2070135330 cites W2064367138 @default.
- W2070135330 cites W2070736155 @default.
- W2070135330 cites W2087496251 @default.
- W2070135330 cites W2093737220 @default.
- W2070135330 cites W2095159575 @default.
- W2070135330 cites W2096345551 @default.
- W2070135330 cites W2104268112 @default.
- W2070135330 cites W2105546584 @default.
- W2070135330 cites W2122590911 @default.
- W2070135330 cites W2142841029 @default.
- W2070135330 cites W2143070723 @default.
- W2070135330 cites W2149325192 @default.
- W2070135330 cites W2150465867 @default.
- W2070135330 cites W2150981663 @default.
- W2070135330 cites W2151214668 @default.
- W2070135330 cites W2154681033 @default.
- W2070135330 cites W2157322512 @default.
- W2070135330 cites W2314597053 @default.
- W2070135330 doi "https://doi.org/10.1021/acs.jpclett.5b00252" @default.
- W2070135330 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26263305" @default.
- W2070135330 hasPublicationYear "2015" @default.
- W2070135330 type Work @default.
- W2070135330 sameAs 2070135330 @default.
- W2070135330 citedByCount "14" @default.
- W2070135330 countsByYear W20701353302015 @default.
- W2070135330 countsByYear W20701353302016 @default.
- W2070135330 countsByYear W20701353302017 @default.
- W2070135330 countsByYear W20701353302018 @default.
- W2070135330 countsByYear W20701353302020 @default.
- W2070135330 countsByYear W20701353302021 @default.
- W2070135330 crossrefType "journal-article" @default.
- W2070135330 hasAuthorship W2070135330A5002067531 @default.
- W2070135330 hasAuthorship W2070135330A5011370114 @default.
- W2070135330 hasAuthorship W2070135330A5014744105 @default.
- W2070135330 hasAuthorship W2070135330A5027872356 @default.
- W2070135330 hasConcept C118792377 @default.
- W2070135330 hasConcept C121332964 @default.
- W2070135330 hasConcept C131631996 @default.
- W2070135330 hasConcept C141071460 @default.
- W2070135330 hasConcept C145148216 @default.
- W2070135330 hasConcept C147597530 @default.
- W2070135330 hasConcept C148093993 @default.
- W2070135330 hasConcept C1491633281 @default.
- W2070135330 hasConcept C149823470 @default.
- W2070135330 hasConcept C159467904 @default.
- W2070135330 hasConcept C161790260 @default.
- W2070135330 hasConcept C171250308 @default.
- W2070135330 hasConcept C178790620 @default.
- W2070135330 hasConcept C185592680 @default.
- W2070135330 hasConcept C192562407 @default.
- W2070135330 hasConcept C2182769 @default.
- W2070135330 hasConcept C2777361361 @default.
- W2070135330 hasConcept C2777619693 @default.
- W2070135330 hasConcept C2779281246 @default.
- W2070135330 hasConcept C513720949 @default.
- W2070135330 hasConcept C55493867 @default.
- W2070135330 hasConcept C59593255 @default.
- W2070135330 hasConcept C68709404 @default.
- W2070135330 hasConcept C71924100 @default.
- W2070135330 hasConcept C74859849 @default.
- W2070135330 hasConcept C97355855 @default.
- W2070135330 hasConcept C99975950 @default.