FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2070136044> ?p ?o ?g. }

• W2070136044 abstract "Abstract Purpose This study was performed to evaluate the potential of a collagen‐based membrane, collagen vitrigel ( CV ), for reconstructing corneal epithelium in the stromal wound and limbal stem cell deficiency ( LSCD ) models. Methods Three groups of rabbits were used in the stromal wound model: CV affixed using fibrin glue ( CV + FG group, n = 9), fibrin glue only ( FG group, n = 3) and an untreated control group ( n = 3). In the LSCD model, one group received CV containing human limbal epithelial cells ( CV + hLEC group, n = 2) and the other was an untreated control ( n = 1). Gross observation, including fluorescent staining, pathological examination, immunohistochemistry and electron microscopy, was used to evaluate the effect of CV on the corneal epithelium. Results In the stromal wound model, fluorescent staining showed that epithelial reconstruction occurred as rapidly in the CV + FG group as it did in the control group. The pathological examination proved that the CV supported a healthy corneal epithelium in the CV + FG group, whereas FG led to hypertrophy and inappropriate differentiation of corneal epithelium in the FG group. In the LSCD model, the corneas in the CV + h LEC group showed sustained tissue transparency with good epithelialization, low inflammatory response and reduced neovascularization. However, the control cornea was translucent and showed high amounts of inflammation and neovascularization. Conclusion We have demonstrated that CV supports corneal epithelial differentiation and prevents epithelial hypertrophy, in addition to serving as a scaffold for h LEC transplantation, without complications." @default.
• W2070136044 created "2016-06-24" @default.
• W2070136044 creator A5000691480 @default.
• W2070136044 creator A5004832736 @default.
• W2070136044 creator A5008468088 @default.
• W2070136044 creator A5010304368 @default.
• W2070136044 creator A5012578051 @default.
• W2070136044 creator A5017494930 @default.
• W2070136044 creator A5031602896 @default.
• W2070136044 creator A5034757001 @default.
• W2070136044 creator A5045326528 @default.
• W2070136044 creator A5088413778 @default.
• W2070136044 date "2014-12-11" @default.
• W2070136044 modified "2023-10-16" @default.
• W2070136044 title "Regeneration of corneal epithelium utilizing a collagen vitrigel membrane in rabbit models for corneal stromal wound and limbal stem cell deficiency" @default.
• W2070136044 cites W1483925966 @default.
• W2070136044 cites W1836265445 @default.
• W2070136044 cites W1926284833 @default.
• W2070136044 cites W1965083225 @default.
• W2070136044 cites W1969148927 @default.
• W2070136044 cites W1970892084 @default.
• W2070136044 cites W1971711041 @default.
• W2070136044 cites W1977674423 @default.
• W2070136044 cites W1982316191 @default.
• W2070136044 cites W1984694191 @default.
• W2070136044 cites W1993333697 @default.
• W2070136044 cites W2002241209 @default.
• W2070136044 cites W2009101760 @default.
• W2070136044 cites W2015863194 @default.
• W2070136044 cites W2018073132 @default.
• W2070136044 cites W2021402105 @default.
• W2070136044 cites W2026545622 @default.
• W2070136044 cites W2027009857 @default.
• W2070136044 cites W2031151230 @default.
• W2070136044 cites W2031721300 @default.
• W2070136044 cites W2031993289 @default.
• W2070136044 cites W2036162319 @default.
• W2070136044 cites W2036607348 @default.
• W2070136044 cites W2040743587 @default.
• W2070136044 cites W2047361071 @default.
• W2070136044 cites W2049461563 @default.
• W2070136044 cites W2051251096 @default.
• W2070136044 cites W2054351923 @default.
• W2070136044 cites W2054710058 @default.
• W2070136044 cites W2069132480 @default.
• W2070136044 cites W2071110385 @default.
• W2070136044 cites W2073486354 @default.
• W2070136044 cites W2074696012 @default.
• W2070136044 cites W2075680739 @default.
• W2070136044 cites W2081261019 @default.
• W2070136044 cites W2088508542 @default.
• W2070136044 cites W2089858022 @default.
• W2070136044 cites W2091758755 @default.
• W2070136044 cites W2114425621 @default.
• W2070136044 cites W2117611251 @default.
• W2070136044 cites W2118596455 @default.
• W2070136044 cites W2123630792 @default.
• W2070136044 cites W2132984034 @default.
• W2070136044 cites W2133723216 @default.
• W2070136044 cites W2141621460 @default.
• W2070136044 cites W2150042936 @default.
• W2070136044 cites W2159972409 @default.
• W2070136044 cites W2161096308 @default.
• W2070136044 cites W2162779554 @default.
• W2070136044 doi "https://doi.org/10.1111/aos.12503" @default.
• W2070136044 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25495158" @default.
• W2070136044 hasPublicationYear "2014" @default.
• W2070136044 type Work @default.
• W2070136044 sameAs 2070136044 @default.
• W2070136044 citedByCount "37" @default.
• W2070136044 countsByYear W20701360442015 @default.
• W2070136044 countsByYear W20701360442016 @default.
• W2070136044 countsByYear W20701360442017 @default.
• W2070136044 countsByYear W20701360442018 @default.
• W2070136044 countsByYear W20701360442019 @default.
• W2070136044 countsByYear W20701360442020 @default.
• W2070136044 countsByYear W20701360442021 @default.
• W2070136044 countsByYear W20701360442022 @default.
• W2070136044 countsByYear W20701360442023 @default.
• W2070136044 crossrefType "journal-article" @default.
• W2070136044 hasAuthorship W2070136044A5000691480 @default.
• W2070136044 hasAuthorship W2070136044A5004832736 @default.
• W2070136044 hasAuthorship W2070136044A5008468088 @default.
• W2070136044 hasAuthorship W2070136044A5010304368 @default.
• W2070136044 hasAuthorship W2070136044A5012578051 @default.
• W2070136044 hasAuthorship W2070136044A5017494930 @default.
• W2070136044 hasAuthorship W2070136044A5031602896 @default.
• W2070136044 hasAuthorship W2070136044A5034757001 @default.
• W2070136044 hasAuthorship W2070136044A5045326528 @default.
• W2070136044 hasAuthorship W2070136044A5088413778 @default.
• W2070136044 hasBestOaLocation W20701360441 @default.
• W2070136044 hasConcept C118487528 @default.
• W2070136044 hasConcept C126322002 @default.
• W2070136044 hasConcept C141071460 @default.
• W2070136044 hasConcept C142724271 @default.
• W2070136044 hasConcept C16930146 @default.
• W2070136044 hasConcept C171056886 @default.
• W2070136044 hasConcept C2776882836 @default.
• W2070136044 hasConcept C2778271429 @default.
• W2070136044 hasConcept C2779257441 @default.

• next