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- W2070176106 abstract "After removal of the gallbladder (cholecystectomy) 7 patients were administered the antirheumatic agent Auranofin in its commercially available tablet form (Ridaura) 3 d postoperative. The single dose consisted of 5 tablets (4.35 mg of gold). Gold was determined in samples of blood, plasma, urine, bile, and feces (1 –2 mL and 2.5 g, respectively). The specimens were drawn 10 min to 8 d p.a. and on d 14 p.a. The determinations were performed by instrumental neutron activation analysis (IN A A). The limit of detection was less than 1 ng of gold. The courses of the mean gold concentrations show maxima after 1.9 h in blood and plasma, and after 16 h in urine and bile. The mean half-lives (terminal phases) are 7.6 d (blood), 23 d (plasma), and 6.5 d (bile)." @default.
- W2070176106 created "2016-06-24" @default.
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- W2070176106 date "1990-01-01" @default.
- W2070176106 modified "2023-09-27" @default.
- W2070176106 title "Whole Body Elimination Routes of Gold in Humans After a Single-Dose Application of the Antirheumatic Auranofin" @default.
- W2070176106 cites W1969923540 @default.
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- W2070176106 doi "https://doi.org/10.1007/978-1-4612-0473-2_51" @default.
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- W2070176106 hasPublicationYear "1990" @default.
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