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- W2070186141 abstract "The hookworm Necator americanus establishes infections of impressive longevity in the immunologically hostile environment of its human host. In the process, it promotes pronounced T-helper 2 (Th2) cell activity, which in turn seemingly affords the host at least a degree of protection. Given the relatively asymptomatic nature of infection, we argue here that Necator americanus might be approaching a mutualistic symbiotic relationship with humans. In our view, infection is controlled by the immune system while being supported by a subtle immune-evasion strategy that is tolerated and possibly beneficial to the host in certain immunological circumstances, such as in counterbalancing potentially damaging Th1 responses." @default.
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- W2070186141 date "1990-07-01" @default.
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- W2070186141 title "The epidemiological significance of the immune response to the cuticular collagen of Necator americanus: A preliminary study in a hookworm-endemic area in Papua New Guinea" @default.
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- W2070186141 doi "https://doi.org/10.1016/0001-706x(90)90042-x" @default.
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