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- W2070191621 abstract "Abstract The emission maximum of human growth hormone, excited at 280 nm, in aqueous solution (pH 7.5) and in the presence of 6 M guanidine is at 348 nm. Rates of increase of tryptophanyl fluorescence of human growth hormone with ethanol or dioxane (up to 30%, by vol.) are identical to those shown by N- acetyl- l - tryptophanamide . Perturbation of tyrosyl fluorescence by ethanol is identical to that of N- acetyl- l - tyrosinamide whereas by dioxane it is only 39%. Tryptophanyl fluorescence of human growth hormone is quenched by about 35% between pH 9 and II in the aqueous solution but not in the presence of 6 M guanidine. These results suggest that the single tryptophanyl residue of human growth hormone is accessible to solvent molecules and may be situated close to tyrosyl residue(s)." @default.
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- W2070191621 date "1972-03-01" @default.
- W2070191621 modified "2023-10-12" @default.
- W2070191621 title "Fluorescence studies of human growth hormone" @default.
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- W2070191621 doi "https://doi.org/10.1016/0005-2795(72)90167-5" @default.
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