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• W2070201691 endingPage "L140" @default.
• W2070201691 startingPage "L130" @default.
• W2070201691 abstract "Although asthma has long been considered a heterogeneous disease, attempts to define subgroups of asthma have been limited. In recent years, both clinical and statistical approaches have been utilized to better merge clinical characteristics, biology, and genetics. These combined characteristics have been used to define phenotypes of asthma, the observable characteristics of a patient determined by the interaction of genes and environment. Identification of consistent clinical phenotypes has now been reported across studies. Now the addition of various 'omics and identification of specific molecular pathways have moved the concept of clinical phenotypes toward the concept of molecular phenotypes. The importance of these molecular phenotypes is being confirmed through the integration of molecularly targeted biological therapies. Thus the global term asthma is poised to become obsolete, being replaced by terms that more specifically identify the pathology associated with the disease." @default.
• W2070201691 created "2016-06-24" @default.
• W2070201691 creator A5040784287 @default.
• W2070201691 creator A5050793109 @default.
• W2070201691 creator A5078918979 @default.
• W2070201691 date "2015-01-15" @default.
• W2070201691 modified "2023-10-15" @default.
• W2070201691 title "Emerging molecular phenotypes of asthma" @default.
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